Objective: To assess whether the association of serum homocysteine concentration with
ischaemic heart disease, deep vein thrombosis and pulmonary embolism, and stroke is …

Background Results from genetic epidemiological studies suggest that raised serum
homocysteine is a cause of ischaemic heart disease, but the results of randomised trials …

ContextIt has been suggested that total blood homocysteine concentrations are associated
with the risk of ischemic heart disease (IHD) and stroke. ObjectiveTo assess the relationship …

An elevated level of plasma total homocysteine is an independent, graded and strong risk
factor for cardiovascular disease, which shows a strong interactive effect with conventional …

Although evidence suggests that the homocysteine hypothesis is still relevant as a predictor
of cardiovascular risk, we cannot conclude that measuring the homocysteine level is useful …

For more than 20 years, moderately raised concentrations of total homocysteine (tHcy) have
been associated with an increased risk of atherothrombotic vascular events but only recently …

The role of homocysteine as a risk factor for cardiovascular disease remains controversial
because positive reports from case–control studies may be the consequence of reverse …

The possibility that raised levels of plasma homocysteine may increase the risk of coronary
heart disease (CHD) has [11, identified 17 epidemiological studies involving a total studies …

Moderately elevated levels of blood total homocysteine have been identified as a potentially
important modifiable risk factor for cardiovascular disease [11. Many studies, conducted in …

A raised plasma level of the amino acid homocysteine is associated with increased risk of
cardiovascular disease. This association may be causal—it is biologically plausible, fairly …