Background The erythrocytic stage of the life cycle of the malaria parasite, Plasmodium
falciparum, consists of trophozoite, schizont and gametocyte stages in humans. Various anti …

The roots, leaves and stems of Christia vespertilionis were separately and successively
extracted with methanol and aqueous-methanol (1: 4, v/v) and were evaluated in vitro for …

Croton linearis is a shrub that grows in Caribbean regions, which is rich in metabolites such
as alkaloids. The main aim of this study was to evaluate the antiplasmodial effect of alkaloids …

The absence of a vaccine and the rampant resistance to almost all antimalarial drugs have
accentuated the urgent need for new antimalarial drugs and drug targets for both …

Activity guided fractionation of extracts from Clausena harmandiana have led to the
identification of four known compounds, heptaphylline (1), clausine K (2), dentatin (5), and …

According to the WHO, in 2008, there were 247 million reported cases of malaria and nearly
one million deaths from the disease. Parasite resistance against first-line drugs, including …

The in vitro antiplasmodial activity of Ambrosia tenuifolia organic extract and its isolated
sesquiterpene lactones, psilostachyin and peruvin, has been evaluated against Plasmodium …

Ethnopharmacological relevance Cissampelos pareira is used traditionally in India as a
remedy for the treatment of various diseases including malaria but the active ingredients …

Background Discovery of novel gametocytocidal molecules is a major pharmacological
strategy in the elimination and eradication of malaria. The high patronage of the aqueous …

Background: Drugs are an important tool for control of malaria. However, drug resistance is
likely to compromise available antimalarial drugs with time. As a result, efforts are being …