One of the most noticeable effects of aging is the reduction in skeletal muscle mass and
strength (sarcopenia). The metabolic syndrome (MS) is also prevalent in old subjects, but its …

Background. Evidence implicates the amount and location of fat in aging-related loss of
muscle function; however, whether intramyocellular lipids affect muscle contractile capacity …

Background The exact impact of ageing on skeletal muscle phenotype and mitochondrial
and lipid content remains controversial, probably because physical activity, which greatly …

The purpose of this study was to determine whether ultrastructural changes in
intramyocellular lipid (IMCL) and mitochondria occur with aging. Muscle samples were …

Intramyocellular lipid (IMCL) has been associated with insulin resistance. However, an
association between IMCL and insulin resistance might be modulated by oxidative capacity …

Skeletal muscle (SM) plays a central role in many biological functions, such as movement
and metabolism, and alterations in SM mass and composition can have a marked influence …

To assess the age-related loss of muscle mass and to determine the mechanisms behind
this aging atrophy, the muscle structure and fiber type composition have been estimated …

Age-related loss of skeletal muscle mass and function is implicated in the development of
disease and physical disability. However, little is known about how age affects skeletal …

Aging is generally accompanied by a progressive loss of skeletal muscle mass and
impairments in metabolic function. Even a few days of muscle disuse (such as that occurring …

The gastrocnemius muscle (GM) of young (3 months) and aged (12 months) female wild-
type C57/BL6 mice was examined by light and electron microscopy, looking for the presence …