The Perseus computational platform for comprehensive analysis of (prote) omics data

S Tyanova, T Temu, P Sinitcyn, A Carlson, MY Hein… - Nature …, 2016 - nature.com
A main bottleneck in proteomics is the downstream biological analysis of highly multivariate
quantitative protein abundance data generated using mass-spectrometry-based analysis …

[HTML][HTML] Perseus: a bioinformatics platform for integrative analysis of proteomics data in cancer research

S Tyanova, J Cox - Cancer systems biology: Methods and protocols, 2018 - Springer
Mass spectrometry-based proteomics is a continuously growing field marked by
technological and methodological improvements. Cancer proteomics is aimed at pursuing …

SanXoT: a modular and versatile package for the quantitative analysis of high-throughput proteomics experiments

M Trevisan-Herraz, N Bagwan, F García-Marqués… - …, 2019 - academic.oup.com
Mass spectrometry-based proteomics has had a formidable development in recent years,
increasing the amount of data handled and the complexity of the statistical resources …

Advancing translational research and precision medicine with targeted proteomics

AC Uzozie, R Aebersold - Journal of proteomics, 2018 - Elsevier
Remarkable advances in quantitative mass spectrometry have shifted the focus of
proteomics from the characterization of protein expression profiles to detailed investigations …

COMPASS: A suite of pre‐and post‐search proteomics software tools for OMSSA

CD Wenger, DH Phanstiel, MV Lee, DJ Bailey… - …, 2011 - Wiley Online Library
Here we present the Coon OMSSA Proteomic Analysis Software Suite (COMPASS): a free
and open‐source software pipeline for high‐throughput analysis of proteomics data …

[HTML][HTML] GProX, a user-friendly platform for bioinformatics analysis and visualization of quantitative proteomics data

KTG Rigbolt, JT Vanselow, B Blagoev - Molecular & Cellular Proteomics, 2011 - ASBMB
Recent technological advances have made it possible to identify and quantify thousands of
proteins in a single proteomics experiment. As a result of these developments, the analysis …

pyOpenMS: a Python‐based interface to the OpenMS mass‐spectrometry algorithm library

HL Röst, U Schmitt, R Aebersold, L Malmström - Proteomics, 2014 - Wiley Online Library
pyOpenMS is an open‐source, Python‐based interface to the C++ OpenMS library,
providing facile access to a feature‐rich, open‐source algorithm library for MS‐based …

DanteR: an extensible R-based tool for quantitative analysis of-omics data

T Taverner, YV Karpievitch, AD Polpitiya… - …, 2012 - academic.oup.com
Motivation: The size and complex nature of mass spectrometry-based proteomics datasets
motivate development of specialized software for statistical data analysis and exploration …

Quantitative proteomics: challenges and opportunities in basic and applied research

OT Schubert, HL Röst, BC Collins, G Rosenberger… - Nature protocols, 2017 - nature.com
In this Perspective, we discuss developments in mass-spectrometry-based proteomic
technology over the past decade from the viewpoint of our laboratory. We also reflect on …

[HTML][HTML] Bioinformatics analysis of mass spectrometry-based proteomics data sets

C Kumar, M Mann - FEBS letters, 2009 - Elsevier
Proteomics has made tremendous progress, attaining throughput and comprehensiveness
so far only seen in genomics technologies. The consequent avalanche of proteome level …