[HTML][HTML] Linking brain age gap to mental and physical health in the Berlin aging study II

P Jawinski, S Markett, J Drewelies, S Düzel… - Frontiers in Aging …, 2022 - frontiersin.org
From a biological perspective, humans differ in the speed they age, and this may manifest in
both mental and physical health disparities. The discrepancy between an individual's …

[HTML][HTML] Bio-psycho-social factors' associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants

M Korbmacher, TP Gurholt, AMG de Lange… - Frontiers in …, 2023 - frontiersin.org
Brain age refers to age predicted by brain features. Brain age has previously been
associated with various health and disease outcomes and suggested as a potential …

[HTML][HTML] Accelerated MRI-predicted brain ageing and its associations with cardiometabolic and brain disorders

A Kolbeinsson, S Filippi, Y Panagakis, PM Matthews… - Scientific Reports, 2020 - nature.com
Brain structure in later life reflects both influences of intrinsic aging and those of lifestyle,
environment and disease. We developed a deep neural network model trained on brain MRI …

[HTML][HTML] Health-related heterogeneity in brain aging and associations with longitudinal change in cognitive function

J Wrigglesworth, J Ryan, PGD Ward… - Frontiers in Aging …, 2023 - frontiersin.org
Neuroimaging-based 'brain age'can identify individuals with 'advanced'or 'resilient'brain
aging. Brain-predicted age difference (brain-PAD) is predictive of cognitive and physical …

[HTML][HTML] Multimodality neuroimaging brain-age in UK biobank: relationship to biomedical, lifestyle, and cognitive factors

JH Cole - Neurobiology of aging, 2020 - Elsevier
The brain-age paradigm is proving increasingly useful for exploring aging-related disease
and can predict important future health outcomes. Most brain-age research uses structural …

Individual variations in 'brain age'relate to early-life factors more than to longitudinal brain change

D Vidal-Pineiro, Y Wang, SK Krogsrud, IK Amlien… - elife, 2021 - elifesciences.org
Brain age is a widely used index for quantifying individuals' brain health as deviation from a
normative brain aging trajectory. Higher-than-expected brain age is thought partially to …

[HTML][HTML] Gender-specific impact of personal health parameters on individual brain aging in cognitively unimpaired elderly subjects

K Franke, M Ristow, C Gaser… - Frontiers in aging …, 2014 - frontiersin.org
Aging alters brain structure and function. Personal health markers and modifiable lifestyle
factors are related to individual brain aging as well as to the risk of developing Alzheimer's …

Brain-predicted age difference score is related to specific cognitive functions: a multi-site replication analysis

R Boyle, L Jollans, LM Rueda-Delgado, R Rizzo… - Brain imaging and …, 2021 - Springer
Brain-predicted age difference scores are calculated by subtracting chronological age from
'brain'age, which is estimated using neuroimaging data. Positive scores reflect accelerated …

[HTML][HTML] Brain age predicts mortality

JH Cole, SJ Ritchie, ME Bastin, V Hernández… - Molecular …, 2018 - nature.com
Age-associated disease and disability are placing a growing burden on society. However,
ageing does not affect people uniformly. Hence, markers of the underlying biological ageing …

Sex differences in predictors and regional patterns of brain age gap estimates

N Sanford, R Ge, M Antoniades… - Human Brain …, 2022 - Wiley Online Library
The brain‐age‐gap estimate (brainAGE) quantifies the difference between chronological
age and age predicted by applying machine‐learning models to neuroimaging data and is …