Stroke, a neurological disease, is one of the leading causes of death worldwide, resulting in
long-term disability in most survivors. Annual stroke costs in the United States alone were …

Significant advances have been made over the past few years concerning the cellular and
molecular events underlying ischemic cell death. The brain succumbs to ischemic injury as a …

Stroke is one of the leading causes of death and severe disability in most industrialized
countries. Despite the extensive research efforts of both academic and industrial …

The management of acute ischemic stroke has not made significant strides since the
introduction of recombinant tissue plasminogen activator (r-TPA) two decades ago. The use …

Stroke occurs when a cerebral blood vessel is blocked or ruptured, and it is the major cause
of death and adult disability worldwide. Various pharmacological agents have been …

Ischemic stroke triggers a complex and highly interconnected cascade of cellular and
molecular events. Early events induced following ischemic injury, including excitotoxicity …

Stroke is the second leading cause of death and a major contributor to disability worldwide.
The prevalence of stroke is highest in developing countries, with ischemic stroke being the …

Cerebral ischemia (stroke) triggers a complex series of biochemical and molecular
mechanisms that impairs the neurologic functions through breakdown of cellular integrity …

Over the past 20 years, an estimated $1 billion has been spent in research and development
of stroke therapeutics; however, this huge investment has failed to produce a clinically …

Ischemic stroke occurs when the arteries supplying blood to the brain are narrowed or
blocked, inducing damage to brain tissue due to a lack of blood supply. One effective way to …