Healthy babies after intrauterine transfer of mosaic aneuploid blastocysts

E Greco, MG Minasi, F Fiorentino - New England Journal of …, 2015 - Mass Medical Soc
Healthy Babies after Intrauterine Transfer of Mosaic Aneuploid Blastocysts | New England Journal
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Birth of a healthy infant after preimplantation confirmation of euploidy by comparative genomic hybridization

L Wilton, R Williamson, J McBain… - New England Journal …, 2001 - Mass Medical Soc
Embryos that are transferred after in vitro fertilization frequently fail to implant in the uterus; in
many cases, this failure is due to chromosomal abnormalities in the embryo. The current …

The frequency and developmental capability of human embryos containing multinucleated blastomeres.

H Balakier, K Cadesky - Human reproduction (Oxford, England), 1997 - academic.oup.com
The frequency of multinucleated blastomeres (MNB) in 2-and 4-cell stage human embryos
was recorded immediately before embryo transfer using a high-power inverted microscope …

Analysis of implantation and ongoing pregnancy rates following the transfer of mosaic diploid–aneuploid blastocysts

E Fragouli, S Alfarawati, K Spath, D Babariya… - Human genetics, 2017 - Springer
Preimplantation genetic testing for aneuploidy (PGT-A) is widely used in IVF and aims to
improve outcomes by avoiding aneuploid embryo transfers. Chromosomal mosaicism is …

Aneuploidy in the human blastocyst

E Fragouli, D Wells - Cytogenetic and genome research, 2011 - karger.com
Studies of human cleavage stage embryos, 3 days after fertilization of the oocyte, have
revealed remarkably high levels of chromosome abnormality. In addition to meiotic errors …

[HTML][HTML] One hundred mosaic embryos transferred prospectively in a single clinic: exploring when and why they result in healthy pregnancies

AR Victor, JC Tyndall, AJ Brake, LT Lepkowsky… - Fertility and sterility, 2019 - Elsevier
Objective To investigate the parameters of mosaicism and the biological mechanisms
leading to healthy pregnancies from mosaic embryo transfers. Design Prospective study …

[HTML][HTML] Diagnosis and clinical management of embryonic mosaicism

NM Sachdev, SM Maxwell, AG Besser, JA Grifo - Fertility and Sterility, 2017 - Elsevier
Embryonic mosaicism occurs when two or more cell populations with different genotypes are
present within the same embryo. New diagnostic techniques for preimplantation genetic …

Blastocyst-ET and monozygotic twinning

B Behr, JD Fisch, C Racowsky, K Miller, TB Pool… - Journal of assisted …, 2000 - Springer
Purpose: To examine the rate of monozygotic twinning associatedwith blastocyst transfer
using commercially available, cell-free culture systems with unmanipulated blastocysts …

Observations on 767 clinical pregnancies and 500 births after human in-vitro fertilization

PC Steptoe, RG Edwards, DE Walters - Human Reproduction, 1986 - academic.oup.com
Details of 767 clinical pregnancies and 500 births from Bourn Hall are reported. All treated
patients included some over 40 years old, many with ovarian or uterine defects, male …

Embryos cultured in vitro with multinucleated blastomeres have poor implantation potential in human in-vitro fertilization and intracytoplasmic sperm injection.

MJ Pelinck, M De Vos, M Dekens… - Human …, 1998 - academic.oup.com
The aim of the present study was to investigate pregnancy rates ensuing from transfer of
embryos with multinucleated blastomeres. In our in-vitro fertilization (IVF)/intracytoplasmic …