Should I stay or should I go? Golgi membrane spatial organization for protein sorting and retention

P Lujan, F Campelo - Archives of biochemistry and biophysics, 2021 - Elsevier
The Golgi complex is the membrane-bound organelle that lies at the center of the secretory
pathway. Its main functions are to maintain cellular lipid homeostasis, to orchestrate protein …

Mechanisms of transport through the Golgi complex

CL Jackson - Journal of cell science, 2009 - journals.biologists.com
The Golgi complex is the central sorting and processing station of the secretory pathway,
ensuring that cargo proteins, which are synthesized in the endoplasmic reticulum, are …

Journeys through the Golgi—taking stock in a new era

S Emr, BS Glick, AD Linstedt… - Journal of Cell …, 2009 - rupress.org
The Golgi apparatus is essential for protein sorting and transport. Many researchers have
long been fascinated with the form and function of this organelle. Yet, despite decades of …

Transport and sorting in the Golgi complex: multiple mechanisms sort diverse cargo

G Boncompain, AV Weigel - Current opinion in cell biology, 2018 - Elsevier
At the center of the secretory pathway, the Golgi complex ensures correct processing and
sorting of cargos toward their final destination. Cargos are diverse in topology, function and …

Mechanisms of protein retention in the Golgi

DK Banfield - Cold Spring Harbor perspectives in biology, 2011 - cshperspectives.cshlp.org
The protein composition of the Golgi is intimately linked to its structure and function. As the
Golgi serves as the major protein-sorting hub for the secretory pathway, it faces the unique …

Golgi membrane dynamics

JF Presley, C Smith, K Hirschberg, C Miller… - Molecular biology of …, 1998 - Am Soc Cell Biol
The organization and function of the Golgi complex has intrigued cell biologists for many
years (Farquhar and Palade, 1998; Mazzarello and Bentaivoglio, 1998). This is due both to …

[HTML][HTML] Transport through the Golgi apparatus by rapid partitioning within a two-phase membrane system

GH Patterson, K Hirschberg, RS Polishchuk, D Gerlich… - Cell, 2008 - cell.com
The prevailing view of intra-Golgi transport is cisternal progression, which has a key
prediction—that newly arrived cargo exhibits a lag or transit time before exiting the Golgi …

[HTML][HTML] The Golgi complex: a hub of the secretory pathway

K Park, S Ju, N Kim, SY Park - BMB reports, 2021 - ncbi.nlm.nih.gov
The Golgi complex plays a central role in protein secretion by regulating cargo sorting and
trafficking. As these processes are of functional importance to cell polarity, motility, growth …

Intra‐Golgi Transport: Roles for Vesicles, Tubules, and Cisternae

JA Martínez-Menárguez - International Scholarly Research …, 2013 - Wiley Online Library
The Golgi complex is considered the central station of the secretory pathway where cargo
proteins and lipids are properly modified, classified, packed into specific carriers and …

Lipid‐dependent coupling of secretory cargo sorting and trafficking at the trans‐Golgi network

J von Blume, A Hausser - FEBS letters, 2019 - Wiley Online Library
In eukaryotic cells, the trans‐Golgi network (TGN) serves as a platform for secretory cargo
sorting and trafficking. In recent years, it has become evident that a complex network of lipid …