[HTML][HTML] RNA-based therapies: a cog in the wheel of lung cancer defense
Lung cancer (LC) is a heterogeneous disease consisting mainly of two subtypes, non-small
cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and remains the leading …
cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and remains the leading …
Non-small cell lung carcinoma: An overview on targeted therapy
AV Nascimento, H Bousbaa, D Ferreira… - Current drug …, 2015 - ingentaconnect.com
Non-small cell lung cancer (NSCLC) represents close to 90% of all lung cancers. When
diagnosed, most cases are on an advanced and inoperable stage, with limited therapeutic …
diagnosed, most cases are on an advanced and inoperable stage, with limited therapeutic …
[HTML][HTML] MiRNA-based therapies for lung cancer: Opportunities and challenges?
H Yang, Y Liu, L Chen, J Zhao, M Guo, X Zhao, Z Wen… - Biomolecules, 2023 - mdpi.com
Lung cancer is a commonly diagnosed cancer and the leading cause of cancer-related
deaths, posing a serious health risk. Despite new advances in immune checkpoint and …
deaths, posing a serious health risk. Despite new advances in immune checkpoint and …
Therapeutic targeting of non-coding RNAs in cancer
O Slaby, R Laga, O Sedlacek - Biochemical journal, 2017 - portlandpress.com
The majority of the human genome encodes RNAs that do not code for proteins. These non-
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …
[HTML][HTML] Long non-coding RNAs as emerging targets in lung cancer
J Gencel-Augusto, W Wu, TG Bivona - Cancers, 2023 - mdpi.com
Simple Summary Long non-coding RNAs (LncRNAs) are non-protein coding molecules
longer than 200 nucleotides. They play essential roles in normal cell function and …
longer than 200 nucleotides. They play essential roles in normal cell function and …
MicroRNA-targeted therapeutics for lung cancer treatment
J Xue, J Yang, M Luo, WC Cho, X Liu - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Lung cancer is one of the leading causes of cancer-related mortality worldwide.
MicroRNAs (miRNAs) are endogenous non-coding small RNAs that repress the expression …
MicroRNAs (miRNAs) are endogenous non-coding small RNAs that repress the expression …
[HTML][HTML] Insight into the prospects for RNAi therapy of cancer
Z Tian, G Liang, K Cui, Y Liang, Q Wang, S Lv… - Frontiers in …, 2021 - frontiersin.org
RNA interference (RNAi), also known as gene silencing, is a biological process that
prevents gene expression in certain diseases such as cancer. It can be used to improve the …
prevents gene expression in certain diseases such as cancer. It can be used to improve the …
[HTML][HTML] miRNAs and lncRNAs as novel therapeutic targets to improve cancer immunotherapy
Simple Summary Cancer onset and progression are promoted by high deregulation of the
immune system. Recently, major advances in molecular and clinical cancer immunology …
immune system. Recently, major advances in molecular and clinical cancer immunology …
[HTML][HTML] RNA-based therapeutics: current developments in targeted molecular therapy of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a highly heterogeneous and aggressive cancer that
has the highest mortality rate out of all breast cancer subtypes. Conventional clinical …
has the highest mortality rate out of all breast cancer subtypes. Conventional clinical …
[HTML][HTML] RNAi therapeutic platforms for lung diseases
Y Fujita, F Takeshita, K Kuwano, T Ochiya - Pharmaceuticals, 2013 - mdpi.com
RNA interference (RNAi) is rapidly becoming an important method for analyzing gene
functions in many eukaryotes and holds promise for the development of therapeutic gene …
functions in many eukaryotes and holds promise for the development of therapeutic gene …