Surface properties can profoundly impact the bulk and interfacial behavior of pharmaceutical
solids, and also their manufacturability, processability in drug product processes, dissolution …

Powders are complex systems and so pharmaceutical solids are not the exception.
Nowadays, pharmaceutical ingredients must comply with well-defined draconian …

The aim of this study was to investigate the applicability of surface energy characterization
tools such as inverse gas chromatography for the analysis of binary systems. Drug …

Inverse gas chromatography (IGC) is a versatile, powerful, sensitive and relatively fast
technique for characterizing the physicochemical properties of materials. Due to its …

Powders are complex systems with more than one value for surface energy. The presence of
different faces, defects, physical forms and impurities will alter the surface properties. There …

Purpose. Inverse gas chromatography (IGC) is rapidly gaining popularity as a method for
assessing powder surface energy. It is vital to understand what IGC measures if results are …

The behavior of pharmaceutical solids, during either processing or use, can be noticeably
affected by the surface energetics of the constituent particles. Several techniques exist to …

Inverse gas chromatography (IGC) has been employed as a research tool for decades.
Despite this record of use and proven utility in a variety of applications, the technique is not …

This study investigates the impact of micronization on the measured surface energy
characteristics of an active pharmaceutical ingredient (API), Ibipinabant, by inverse gas …

The aim of this study was to investigate the effect of processing route (ie, quench cooling
and ball milling) on the surface energy heterogeneity and surface chemistry of indomethacin …