Enzymatic mineralization has become an effective approach to enhancing the stiffness of
hydrogels for bone tissue engineering, but generally with limited toughness. On the other …

Enzymatic mineralization is an advanced mineralization method that is often used to
enhance the stiffness and strength of hydrogels, but often accompanied by brittle behavior …

The development of hydrogels for bone regeneration has highlighted the challenge that load-
bearing hydrogels need to be biocompatible while achieving high strength. Several …

Bone defects are usually caused by trauma, infection, tumor resection or congenital
diseases, and they attract many researchers' attention to fabricate biomaterials to promote …

Mineralized hydrogels have attracted significant attention in the field of bone repair. Herein,
an innovative strategy of “freezing, salting‐out and mineralizing”(FSM) is proposed for the …

Methods: In this study, we synthesized an organic-inorganic hybrid hydrogel with ultrahigh
strength, stiffness, and toughness via enzyme-induced mineralization of calcium phosphate …

Due to the soft and wet characteristics of hydrogels that acquire high mechanical strength by
toughening strategies, tough and robust hydrogels are attractive as next-generation …

The preparation of high-performance hydrogels from biocompatible materials via a facile
process has been increasingly studied but remains challenging. Herein, a nonswellable and …

Tissue engineering is a promising alternative to autografts, allografts, or biomaterials to
address the treatment of severe and large bone lesions. Classically, tissue engineering …

Bone tissue engineering aims to design mechanically improved macroporous hydrogels
with fibrous topologies using polysaccharides that can provide an appropriate …