Immune-related potential biomarkers and therapeutic targets in coronary artery disease

C Liu, J Liu, Y Zhang, X Wang, Y Guan - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Background Coronary artery disease (CAD) is a complex illness with unknown
pathophysiology. Peripheral biomarkers are a non-invasive method required to track the …

Identification of diagnostic biomarkers and immune cell infiltration in coronary artery disease by machine learning, nomogram, and molecular docking

X Jiang, Y Luo, Z Li, H Zhang, Z Xu… - Frontiers in …, 2024 - frontiersin.org
Background Coronary artery disease (CAD) is still a lethal disease worldwide. This study
aims to identify clinically relevant diagnostic biomarker in CAD and explore the potential …

Integrative analyses of immune-related biomarkers and associated mechanisms in coronary heart disease

L Zhang, G Li, B Liang, X Su, H Xie, H Sun… - BMC Medical …, 2022 - Springer
Various studies showed that the effect of immune activation is pro-atherogenic and coronary
heart disease (CHD) should therefore be considered an autoimmune disease. This study …

Identification of diagnostic biomarkers and therapeutic targets in peripheral immune landscape from coronary artery disease

X Feng, Y Zhang, M Du, S Li, J Ding, J Wang… - Journal of Translational …, 2022 - Springer
Background Peripheral biomarkers are increasingly vital non-invasive methods for
monitoring coronary artery disease (CAD) progression. Their superiority in early detection …

Use of Machine Learning for the Identification and Validation of Immunogenic Cell Death Biomarkers and Immunophenotypes in Coronary Artery Disease

Y Zhang, C Huang, X Zu, J Liu, Y Li - Journal of Inflammation …, 2024 - Taylor & Francis
Objective Immunogenic cell death (ICD) is part of the immune system's response to coronary
artery disease (CAD). In this study, we bioinformatically evaluated the diagnostic and …

Immune Cell Infiltration Analysis Based on Bioinformatics Reveals Novel Biomarkers of Coronary Artery Disease

T He, M Muhetaer, J Wu, J Wan, Y Hu… - Journal of …, 2023 - Taylor & Francis
Background Coronary artery disease (CAD) is a multifactorial immune disease, but research
into the specific immune mechanism is still needed. The present study aimed to identify …

[HTML][HTML] Identification of hub genes and their correlation with immune infiltration in coronary artery disease through bioinformatics and machine learning methods

KK Huang, HL Zheng, S Li, ZY Zeng - Journal of Thoracic Disease, 2022 - ncbi.nlm.nih.gov
Background Coronary artery disease (CAD) is a multifactorial disease and its pathogenesis
remains unclear. We aimed to explore the optimal feature genes (OFGs) for CAD and to …

Identification of potential therapeutic targets for atherosclerosis by analysing the gene signature related to different immune cells and immune regulators in …

Y Shen, L Xu, X Tang, C Lin, D Yan, S Xue… - BMC Medical …, 2021 - Springer
Background Atherosclerosis is a chronic inflammatory disease that affects multiple arteries.
Numerous studies have shown the inherent immune diversity in atheromatous plaques and …

Immune-associated gene signatures and subtypes to predict the progression of atherosclerotic plaques based on machine learning

Y Yang, X Yi, Y Cai, Y Zhang, Z Xu - Frontiers in pharmacology, 2022 - frontiersin.org
Objective: Experimental and clinical evidence suggests that atherosclerosis is a chronic
inflammatory disease. Our study was conducted for uncovering the roles of immune …

Potential of immune-related genes as promising biomarkers for premature coronary heart disease through high throughput sequencing and integrated bioinformatics …

H Wang, J Shao, X Lu, M Jiang, X Li, Z Liu… - Frontiers in …, 2022 - frontiersin.org
Background Coronary heart disease (CHD) is the most common progressive disease that is
difficult to diagnose and predict in the young asymptomatic period. Our study explored a …