Hirschsprung disease (HSCR) is a rare congenital intestinal disease that occurs in 1 in
5,000 live births. HSCR is characterized by the absence of ganglion cells in the myenteric …

Background/purpose Understanding the true nature of the disease provided the basis for
appropriate surgery for Hirschsprung's disease some 60 years ago. Nevertheless, surgical …

Hirschsprung's disease (HSCR) is characterized by absence of the enteric nervous system
in a variable portion of the distal gut. Affected infants usually present in the days after birth …

Hirschsprung's disease (HSCR) is a complex congenital disorder which, from a molecular
perspective, appears to result due to disruption of normal signalling during development of …

Hirschsprung disease (HSCR) is the leading cause of neonatal functional intestinal
obstruction. It is a rare congenital disease with an incidence of one in 3,500–5,000 live …

Hirschsprung's disease (congenital megacolon) is caused by the failed migration of colonic
ganglion cells during gestation. Varying lengths of the distal colon are unable to relax …

Hirschsprung disease (HSCR) is a multigenic condition with variable presentation. Most
commonly, it presents in the neonatal period as a functional intestinal obstruction secondary …

Hirschsprung disease (HSCR), which is also called congenital megacolon or intestinal
aganglionosis, is characterized by an absence of enteric (intrinsic) neurons from variable …

Hirschsprung disease (HSCR), or congenital intestinal aganglionosis, is a relatively
common disorder of neural crest migration. It has a strong genetic basis, although simple …

BACKGROUND Hirschsprung disease (HSCR) is a frequent congenital disorder with an
incidence of 1 in 5000 live births, characterised by the absence of parasympathetic …