Context Considerable controversy exists regarding the association of omega-3
polyunsaturated fatty acids (PUFAs) and major cardiovascular end points. Objective To …

Importance Current guidelines advocate the use of marine-derived omega-3 fatty acids
supplements for the prevention of coronary heart disease and major vascular events in …

Background Although omega-3 fatty acids have well documented properties which would
reduce the cardiovascular (CV) disease risk, the evidence from randomized controlled trials …

Background Epidemiologic data suggest that omega‐3 fatty acids derived from fish oil
reduce cardiovascular disease. The clinical benefit of dietary fish oil supplementation in …

Background The clinical benefits of omega-3 fatty acids (FAs) supplementation in preventing
and treating coronary heart disease (CHD) remain controversial. Therefore, this study aimed …

Opinion statement Early secondary prevention trials of fish and omega-3 polyunsaturated
fatty acid (PUFA) capsules reported beneficial effects on cardiovascular disease (CVD) …

The recent publication of the REDUCE-IT study has reopened the debate about the efficacy
of omega-3 fatty acids in reducing the risk of cardiovascular (CV) events. This meta-analysis …

Background—Early trials evaluating the effect of omega 3 fatty acids (ω-3 FA) reported
benefits for mortality and cardiovascular events but recent larger studies trials have variable …

Introduction: Cardiovascular disease remains the commonest health problem in developed
countries, and residual risk after implementing all current therapies is still high. The use of …

Multiple randomized controlled trials (RCTs) have assessed the effects of supplementation
with eicosapentaenoic acid plus docosahexaenoic acid (omega-3 polyunsaturated fatty …