Neurodegenerative diseases (NDs) affect the West due to the increase in life expectancy.
Nervous cells accumulate oxidative damage, which is one of the factors that triggers and …

The transcription factor Nrf2 (nuclear factor-erythroid 2 p45-related factor 2) play a crucial
role in cellular redox and metabolic system. Activation of Nrf2 may be an effective …

Background Nuclear factor erythroid 2-related factor 2 (Nrf2) is a classical nuclear
transcription factor that regulates the system's anti-oxidative stress response. The activation …

Stroke represents one of the main causes of disability and death worldwide. The
pathological subtypes of stroke are ischemic stroke, the most frequent, and hemorrhagic …

Nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) is a basic‐region leucine zipper
transcription factor that regulates the expression of many Phase II detoxifying/antioxidant …

Central nervous system (CNS) trauma, such as traumatic brain injury (TBI) and spinal cord
injury (SCI), represents an increasingly important health burden in view of the preventability …

Neurodegenerative disorders are characterized by progressive loss of neurons. To date, no
efficacious therapies exist for these disorders, and current therapies provide only …

The nuclear factor erythroid-derived 2-related factor 2 (NFE2L2/NRF2) is a master
transcription factor that regulates oxidative stress-related genes containing the antioxidant …

Traumatic brain injury (TBI), known as mechanical damage to the brain, impairs the normal
function of the brain seriously. Its clinical symptoms manifest as behavioral impairment …

Oxidative stress and mitochondrial dysfunction are considered to be major contributing
factors in the development and progression of many neurodegenerative diseases …