Comparison of azvudine, molnupiravir, and nirmatrelvir/ritonavir in adult patients with mild-to-moderate COVID-19: a retrospective cohort study

MP Chen, DX Jiang, JX Rang, HB Zhuo, ZG Zhou - Scientific Reports, 2024 - nature.com
This study aimed to explore the effectiveness and safety of azvudine, nirmatrelvir/ritonavir,
and molnupiravir in adult patients with mild-to-moderate COVID-19. This retrospective cohort …

Is azvudine comparable to nirmatrelvir-ritonavir in real-world efficacy and safety for hospitalized patients with COVID-19? A retrospective cohort study

Q Zhao, B Zheng, B Han, P Feng, Z Xia, H Jiang… - Infectious Diseases and …, 2023 - Springer
Introduction Azvudine and nirmatrelvir-ritonavir are more extensively used to treat COVID-19
in China due to their earlier approval by the National Medical Products Administration …

Head-to-head comparison of azvudine and nirmatrelvir/ritonavir for the hospitalized patients with COVID-19: a real-world retrospective cohort study with propensity …

AH Wei, L Zeng, L Wang, L Gui, WT Zhang… - Frontiers in …, 2023 - frontiersin.org
Background: Nirmatrelvir/ritonavir and azvudine have been approved for the early treatment
of COVID-19 in China, however, limited real-world data exists regarding their effectiveness …

Comparison of Azvudine and Nirmatrelvir/Ritonavir and Combined Use in Patients with COVID-19

CY Hu, WS Cui, Y Lei, YW Tang, YY Zhang… - Infection and Drug …, 2023 - Taylor & Francis
Purpose To compare the effectiveness of azvudine and nirmatrelvir/ritonavir for the treatment
of coronavirus disease (COVID-19). Patients and Methods We conducted a retrospective …

Real‐world effectiveness of Azvudine versus nirmatrelvir–ritonavir in hospitalized patients with COVID‐19: A retrospective cohort study

G Deng, D Li, Y Sun, L Jin, Q Zhou… - Journal of Medical …, 2023 - Wiley Online Library
Chinese guidelines prioritize the use of Azvudine and nirmatrelvir–ritonavir in COVID‐19
patients. Nevertheless, the real‐world effectiveness of Azvudine versus nirmatrelvir–ritonavir …

Real-world effectiveness of nirmatrelvir-ritonavir versus azvudine in hospitalized patients with COVID-19 during the omicron wave in Beijing: a multicenter …

X Han, D Gao, C Li, X Yuan, J Cui, W Zhao, F Xie… - BMC Infectious …, 2024 - Springer
Background and aim Two oral antivirals (Nirmatrelvir-ritonavir and Azvudine) are widely
used in China practice during the Omicron wave of the pandemic. However, little evidence …

Effectiveness and safety of azvudine in older adults with mild and moderate COVID-19: a retrospective observational study

Z Zhou, H Zheng, G Xiao, X Xie, J Rang… - BMC Infectious …, 2024 - Springer
Background Azvudine has clinical benefits and acceptable safety against COVID-19,
including in patients with comorbidities, but there is a lack of available data for its use in …

Azvudine and nirmatrelvir–ritonavir in hospitalized patients with moderate‐to‐severe COVID‐19: Emulation of a randomized target trial

Y Zhou, Y Liu, L Jiang, R Zhang… - Journal of Medical …, 2023 - Wiley Online Library
To examine the effectiveness of azvudine and nirmatrelvir–ritonavir in treating hospitalized
patients with moderate‐to‐severe COVID‐19. We emulated a target trial with a multicenter …

Effectiveness of molnupiravir vs nirmatrelvir-ritonavir in non-hospitalised and hospitalised patients with COVID-19: a target trial emulation study

EYF Wan, VKC Yan, ZCT Wong, CSL Chui… - …, 2023 - thelancet.com
Background Molnupiravir and nirmatrelvir-ritonavir have emerged as promising options for
COVID-19 treatment, but direct comparisons of their effectiveness have been limited. This …

Antiviral efficacy of molnupiravir versus ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19 (PLATCOV): an open-label, phase 2, randomised …

WHK Schilling, P Jittamala, JA Watson… - The Lancet Infectious …, 2024 - thelancet.com
Background Molnupiravir and ritonavir-boosted nirmatrelvir are the two leading oral COVID-
19 antiviral treatments, but their antiviral activities in patients have not been compared …