[HTML][HTML] COVID-19 and sulfonylureas: A reminder of the pleiotropic actions of an old class of drugs just before their swansong

T Koufakis, DS Popovic, S Metallidis, K Kotsa - Metabolism, 2022 - ncbi.nlm.nih.gov
Sulfonylureas (SUs) have been used for the treatment of hyperglycemia for more than 60
years and are currently the second most commonly prescribed antidiabetic agents …

The Effect of Antihyperglycemic Medications on COVID-19: A Meta-analysis and Systematic Review from Observational Studies

ZH Song, QM Huang, SS Xu, JB Zhou… - Therapeutic Innovation & …, 2024 - Springer
Background Diabetes, a chronic disease worldwide, may be associated with a poorer
prognosis in patients with coronavirus disease 2019 (COVID-19). While some …

Sodium–glucose cotransporter 2 inhibitors and major COVID-19 outcomes: promising mechanisms, conflicting data, and intriguing clinical decisions

D Patoulias, C Papadopoulos, A Katsimardou… - Diabetes Therapy, 2020 - Springer
Dear Editor, In their anecdotal report, Bossi and colleagues demonstrate that ''off-label''use
of sodium–glucose cotransporter2 (SGLT2) inhibitors in three subjects with severe or critical …

Mechanisms and potential roles of glucose-lowering agents in COVID-19: a review

HD Berlie, PB Kale-Pradhan… - Annals of …, 2021 - journals.sagepub.com
Objective: To explore mechanistic benefits of glucose-lowering agents that extend beyond
glycemic control with the potential to mitigate coronavirus disease 2019 (COVID-19) …

Sodium-glucose cotransporter 2 inhibitors in the era of COVID-19 pandemic: is the benefit to risk ratio still favorable?

T Koufakis, S Metallidis, P Zebekakis… - Journal of Diabetes …, 2020 - journals.sagepub.com
However, there is a strong counter-argument to this; a number of preclinical studies have
highlighted the potential of SGLT2i to ameliorate systemic and tissue-specific inflammation …

Sodium-glucose co-transporter 2 inhibitors in COVID-19: Meeting at the crossroads between heart, diabetes and infectious diseases

T Koufakis, AN Pavlidis, S Metallidis… - International Journal of …, 2021 - Springer
Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are a new class of glucose-lowering
agents which have changed the landscape of diabetes therapy, due to their remarkable …

A Response To: Sodium–Glucose Cotransporter 2 Inhibitors and Major COVID-19 Outcomes: Promising Mechanisms, Conflicting Data, and Intriguing Clinical …

AC Bossi, F Forloni, PL Colombelli - Diabetes Therapy, 2020 - Springer
Sir, The observations provided in the letter ''Sodium–glucose cotransporter 2 inhibitors
[SGLT2-i] and major COVID-19 outcomes: promising mechanisms, conflicting data, and …

[HTML][HTML] COVID-19 and sodium-glucose cotransporter 2 inhibitors: no fear to attempt?

S Papachristou, T Penlioglou… - Experimental and …, 2022 - thieme-connect.com
Novel coronavirus infectious disease (COVID-19) has been recognised as a pandemic by
the World Health Organization (WHO) 1. Mortality and morbidity are higher in elderly …

Association of anti-diabetic drugs and COVID-19 outcomes in patients with diabetes mellitus type 2 and cardiomyopathy

J Dimnjaković, T Buble, P Ivanko, I Pristaš… - Scientific Reports, 2024 - nature.com
There is a scarcity of information on the population with diabetes mellitus type 2 and
cardiomyopathy (PDMC) in COVID-19, especially on the association between anti-diabetic …

Sodium‐glucose co‐transporter‐2 inhibitors and susceptibility to COVID‐19: a population‐based retrospective cohort study

C Sainsbury, J Wang, K Gokhale… - Diabetes, Obesity …, 2021 - Wiley Online Library
Abstract Sodium‐glucose co‐transporter‐2 (SGLT2) inhibitors are widely prescribed in
people with type 2 diabetes. We aimed to investigate whether SGLT2 inhibitor prescription is …