Angiotensin‐converting enzyme inhibitors and stroke risk: benefit beyond blood pressure reduction?

DE Hilleman, BD Lucas Jr - Pharmacotherapy: The Journal of …, 2004 - Wiley Online Library
Hypertension, a leading cause of morbidity and mortality, accounts for 25–49% of all strokes.
Randomized placebo‐controlled trials primarily with diuretics and β‐blockers administered …

Angiotensin-converting enzyme inhibitors and calcium channel blockers for coronary heart disease and stroke prevention

P Verdecchia, G Reboldi, F Angeli, R Gattobigio… - …, 2005 - Am Heart Assoc
We investigated whether protection from coronary heart disease (CHD) and stroke conferred
by angiotensin-converting enzyme inhibitors (ACEIs) and calcium channel blockers (CCBs) …

Role of antihypertensive therapy with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in combination with calcium channel blockers for …

RL Talbert - Journal of the American Pharmacists Association, 2010 - Elsevier
Objective To review the available literature on the effects of angiotensin-converting enzyme
inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), and calcium channel blockers …

Can the renin‐angiotensin system protect against stroke? A focus on angiotensin II receptor blockers

BJ Epstein, JG Gums - Pharmacotherapy: The Journal of …, 2005 - Wiley Online Library
From a patient's perspective, stroke is the most devastating form of cardiovascular disease,
representing the number one cause of permanent disability in the United States. Treatment …

Could angiotensin II type I receptor antagonists have a superior beneficial effect than that of angiotensin II converting enzyme inhibitors with respect to the risk of …

A Fournier, JM Achard, H Mazouz, A Pruna… - … des Maladies du …, 1999 - europepmc.org
In contrast with the expected results, the Captopril Prevention Project study has found that
the relative risk of stroke was greater by 25% in patients treated with ACEI than in patients …

Comparison between angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on the risk of myocardial infarction, stroke and death: a meta …

G Reboldi, F Angeli, C Cavallini, G Gentile… - Journal of …, 2008 - journals.lww.com
Objectives To compare the effects of angiotensin II receptor blockers and angiotensin-
converting enzyme inhibitors on the risk of myocardial infarction, stroke, cardiovascular …

New strategies for prevention of ischemic stroke: the LIFE study

HP Adams Jr - Current neurology and neuroscience reports, 2003 - Springer
New strategies to lower the risk of stroke among highrisk persons are being developed.
Therapies such as cholesterol-lowering medications and newer antihypertensive agents …

Stroke prevention: not all antihypertensive drugs are created equal

FH Messerli, SM Chiadika - Journal of the Renin-Angiotensin …, 2005 - journals.sagepub.com
Reductions in blood pressure (BP) through intervention can significantly reduce the risk of
cardiovascular events in hypertensive patients. However, a number of trials indicate that …

The role of angiotensinconverting enzyme inhibitors in the treatment of hypertension

P Sleight - Current Cardiology Reports, 2001 - Springer
Angiotensin-converting enzyme (ACE) inhibitors continue to find new uses. The Heart
Outcomes Prevention Evaluation study has demonstrated their wide application as a …

The PROGRESS study: rationale and design

B Neal, S MacMahon - Journal of hypertension, 1995 - journals.lww.com
Rationale: Patients with a history of cerebrovascular disease have a very high risk of stroke,
and usual levels of both systolic and diastolic blood pressure are directly and continuously …