Although the clinical demand for bioengineered blood vessels continues to rise, current
options for vascular conduits remain limited. The synergistic combination of emerging …

Blood vessels transport blood to deliver oxygen and nutrients. Vascular diseases such as
atherosclerosis may result in obstruction of blood vessels and tissue ischemia. These …

Tissue engineering holds great promise in regenerative medicine. However, the field of
tissue engineering faces a myriad of difficulties. A major challenge is the necessity to …

This review focuses on the stem cell sources with the potential to be used in vascular tissue
engineering and to promote vascular regeneration. The first clinical studies using tissue …

BACKGROUND Vascular replacement and repair for the treatment of atherosclerotic
disease, infection, and traumatic injury are some of the most commonly performed surgical …

There is a considerable clinical need for alternatives to the autologous vein and artery
tissues used for vascular reconstructive surgeries such as CABG, lower limb bypass …

Tissue engineering of small diameter (< 5 mm) blood vessels is a promising approach for
developing viable alternatives to autologous vascular grafts. It involves in vitro seeding of …

Only a few engineered tissues—skin, cartilage, bladder—have achieved clinical success,
and biomaterials designed to replace more complex organs are still far from commercial …

Other than a few avascular tissues, almost all human tissues are connected to the systemic
circulation via blood vessels that promote metabolism and function. Accordingly, engineered …

The clinical need for improved blood vessel substitutes, especially in small-diameter
applications, drives the field of vascular tissue engineering. The blood vessel has a well …