The ichthyoses are a large, heterogeneous group of skin cornification disorders. They can
be inherited or acquired, and result in defective keratinocyte differentiation and abnormal …

Background The term ichthyosis describes a generalized disorder of cornification
characterized by scaling and/or hyperkeratosis of different skin regions. Mutations in a broad …

The understanding of monogenetic disorders of cornification, including the group of
diseases called ichthyoses, has expanded greatly in recent years. Studies of the aetiology of …

Hereditary ichthyoses are due to mutations on one or both alleles of more than 30 different
genes, mainly expressed in the upper epidermis. Syndromic as well as nonsyndromic forms …

The ichthyoses, also known as disorders of keratinization (DOK), encompass a
heterogeneous group of skin diseases linked by the common finding of abnormal barrier …

Inherited ichthyoses are a group of genetic disorders characterized by generalized dry skin,
scaling and hyperkeratosis, and often associated with erythroderma. These manifestations …

Inherited ichthyoses, defined as the generalized form of Mendelian disorders of cornification,
are characterized by visible scaling and/or hyperkeratosis of most or all of the skin. This …

BACKGROUND: Inherited ichthyoses belong to a large, clinically and etiologically
heterogeneous group of mendelian disorders of cornification, typically involving the entire …

Inherited ichthyoses are classified as Mendelian disorders of cornification (MEDOC), which
are defined on the basis of clinical and genetic features and are mainly divided into non …

Ichthyoses are a heterogeneous group of cornification disorders characterized by a
generalized scaling of the skin. Common types such as ichthyosis vulgaris and X-linked …