The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …

Mucosal surface layers are the critical borders throughout epithelial membranes. These
epithelial cells segregate luminal material from external environments. However, mucosal …

Our body is colonized by more than a hundred trillion commensals, represented by viruses,
bacteria and fungi. This complex interaction has shown that the microbiome system …

The intestine plays an essential role in integrating immunity and nutrient digestion and
absorption. Adjacent intestinal epithelia form tight junctions (TJs) that are essential to the …

The intestinal tract represents the largest interface between the external environment and
the human body. Nutrient uptake mostly happens in the intestinal tract, where the epithelial …

Host health depends on the intestinal homeostasis between the innate/adaptive immune
system and the microbiome. Numerous studies suggest that gut microbiota are constantly …

The interaction between host and external environment mainly occurs in the gastrointestinal
tract, where the mucosal barrier has a critical role in many physiologic functions ranging …

The intestinal mucosa is continuously exposed to a large number of commensal or
pathogenic microbiota and foreign food antigens. The intestinal epithelium forms a dynamic …

Background & Aims The intestinal barrier protects intestinal cells from microbes and
antigens in the lumen—breaches can alter the composition of the intestinal microbiota, the …

The gastrointestinal epithelium forms the boundary between the body and external
environment. It effectively provides a selective permeable barrier that limits the permeation …