Structure of nucleosome-bound human PBAF complex

L Wang, J Yu, Z Yu, Q Wang, W Li, Y Ren… - Nature …, 2022 - nature.com
BAF and PBAF are mammalian SWI/SNF family chromatin remodeling complexes that
possess multiple histone/DNA-binding subunits and create nucleosome-depleted/free …

A structural model of the endogenous human BAF complex informs disease mechanisms

N Mashtalir, H Suzuki, DP Farrell, A Sankar, J Luo… - Cell, 2020 - cell.com
Mammalian SWI/SNF complexes are ATP-dependent chromatin remodeling complexes that
regulate genomic architecture. Here, we present a structural model of the endogenously …

The BAF complex in development and disease

A Alfert, N Moreno, K Kerl - Epigenetics & chromatin, 2019 - Springer
The ATP-dependent chromatin remodelling complex BAF (= mammalian SWI/SNF complex)
is crucial for the regulation of gene expression and differentiation. In the course of evolution …

The sequential phosphorylation of PHF10 subunit of the PBAF chromatin-remodeling complex determines different properties of the PHF10 isoforms

AA Sheynov, VV Tatarskiy Jr, EV Tatarskiy… - Biology …, 2020 - journals.biologists.com
The mammalian PBAF subfamily of SWI/SNF chromatin remodeling complexes plays a wide
role in the regulation of gene expression. PHF10 is a subunit of the signature module of …

Structure and DNA binding analysis of AT‐rich interaction domain present in human BAF‐B specific subunit BAF250b

M Giri, P Gupta, A Maulik, M Gracias… - Protein Science, 2022 - Wiley Online Library
BAF250b and its paralog BAF250a are the DNA‐binding central hub proteins present in BAF‐
B and BAF‐A classes of SWI/SNF chromatin‐remodeling complexes. BAF250b contains an …

PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes

Z Yan, K Cui, DM Murray, C Ling, Y Xue… - Genes & …, 2005 - genesdev.cshlp.org
PBAF and BAF are two chromatin-remodeling complexes of the SWI/SNF family essential for
mammalian transcription and development. Although these complexes share eight identical …

Structural insights into BAF47 and BAF155 complex formation

L Yan, S Xie, Y Du, C Qian - Journal of molecular biology, 2017 - Elsevier
Mammalian BAF complexes are a subfamily of SWI/SNF ATP-dependent chromatin
remodelers that dynamically modulate chromatin structure to regulate fundamental cellular …

A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex

Z Nie, Y Xue, D Yang, S Zhou, BJ Deroo… - … and cellular biology, 2000 - Am Soc Microbiol
The SWI/SNF family of chromatin-remodeling complexes facilitates gene activation by
assisting transcription machinery to gain access to targets in chromatin. This family includes …

Structure of nucleosome-bound human BAF complex

S He, Z Wu, Y Tian, Z Yu, J Yu, X Wang, J Li, B Liu… - Science, 2020 - science.org
Mammalian SWI/SNF family chromatin remodelers, BRG1/BRM-associated factor (BAF) and
polybromo-associated BAF (PBAF), regulate chromatin structure and transcription, and their …

Domain architecture of BAF250a reveals the ARID and ARM-repeat domains with implication in function and assembly of the BAF remodeling complex

S Sandhya, A Maulik, M Giri, M Singh - PLoS One, 2018 - journals.plos.org
BAF250a and BAF250b are subunits of the SWI/SNF chromatin-remodeling complex that
recruit the complex to chromatin allowing transcriptional activation of several genes. Despite …