Medication overuse headache is associated with elevated lipopolysaccharide binding protein and pro-inflammatory molecules in the bloodstream
HG Dağıdır, E Topa, D Vuralli, H Bolay - The Journal of Headache and …, 2023 - Springer
Objective Medication overuse headache (MOH) is a secondary headache that accompanies
chronic migraine. Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most frequently …
chronic migraine. Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most frequently …
Lipopolysaccharide, VE-cadherin, HMGB1, and HIF-1α levels are elevated in the systemic circulation in chronic migraine patients with medication overuse headache …
D Vuralli, M Ceren Akgor, H Gok Dagidir… - The journal of headache …, 2024 - Springer
Objective Medication overuse headache (MOH) was recently shown to be associated with
leaky gut in rodents. We aimed to investigate whether chronic migraine (CM) patients with …
leaky gut in rodents. We aimed to investigate whether chronic migraine (CM) patients with …
Medication-overuse headache and opioid-induced hyperalgesia: A review of mechanisms, a neuroimmune hypothesis and a novel approach to treatment
JL Johnson, MR Hutchinson, DB Williams… - …, 2013 - journals.sagepub.com
Introduction Patients with chronic headache who consume large amounts of analgesics are
often encountered in clinical practice. Excessive intake of analgesics is now considered to …
often encountered in clinical practice. Excessive intake of analgesics is now considered to …
Activation of the microglial P2X7R/NLRP3 inflammasome mediates central sensitization in a mouse model of medication overuse headache
Y Wang, L Dong, Y Zhang, Y Zhang, G Qin… - Frontiers in Molecular …, 2023 - frontiersin.org
Background Excessive use of headache treatments often leads to the development,
progression and exacerbation of primary headache, which is defined as medication overuse …
progression and exacerbation of primary headache, which is defined as medication overuse …
Risk of development of medication overuse headache with nonsteroidal anti-inflammatory drug therapy for migraine: a critically appraised topic
AJ Starling, C Hoffman-Snyder, RB Halker… - The …, 2011 - journals.lww.com
Background: The development of medication overuse headache (MOH) is associated with
frequent use of analgesics, especially opiates, for treatment of primary headache disorders …
frequent use of analgesics, especially opiates, for treatment of primary headache disorders …
[PDF][PDF] Recurrent headache increases blood-brain barrier permeability and VEGF expression in rats
X Mi, R Li, L Chen, G Qin - Pain physician, 2018 - painphysicianjournal.com
Background: The blood-brain barrier (BBB) is an important anatomical structure of the
central nervous system (CNS) that limits the penetration of a variety of substances from the …
central nervous system (CNS) that limits the penetration of a variety of substances from the …
Neural hyperactivity in the amygdala induced by chronic treatment of rats with analgesics may elucidate the mechanisms underlying psychiatric comorbidities …
A Wanasuntronwong, U Jansri, A Srikiatkhachorn - BMC neuroscience, 2017 - Springer
Background Patients with medication-overuse headache suffer not only from chronic
headache, but often from psychiatric comorbidities, such as anxiety and depression. The …
headache, but often from psychiatric comorbidities, such as anxiety and depression. The …
Increased serum levels of interleukin-8 in patients with tension-type headache
RB Domingues, H Duarte, NP Rocha… - …, 2015 - journals.sagepub.com
Background and objectives The pathophysiology of tension-type headache is not well
understood. Increased peripheral levels of pro-inflammatory cytokines may act as mediators …
understood. Increased peripheral levels of pro-inflammatory cytokines may act as mediators …
Pathophysiology of medication overuse headache: insights and hypotheses from preclinical studies
ID Meng, D Dodick, MH Ossipov, F Porreca - Cephalalgia, 2011 - journals.sagepub.com
Introduction: Medication overuse headache (MOH) is a clinical concern in the management
of migraine headache. MOH arises from the frequent use of medications used for the …
of migraine headache. MOH arises from the frequent use of medications used for the …
Salivary inflammatory markers in tension type headache and migraine: the SalHead cohort study
A Bougea, N Spantideas, P Galanis, P Katsika… - Neurological …, 2020 - Springer
Objective To investigate the possible association between salivary CRP, IL-1β, and IL-6
levels, depression/anxiety and migraine, and tension type headache (TTH) in saliva of these …
levels, depression/anxiety and migraine, and tension type headache (TTH) in saliva of these …