F Mangialasche, A Solomon, B Winblad… - The Lancet …, 2010 - thelancet.com
Alzheimer's disease is the most common cause of dementia in elderly people. Research into Alzheimer's disease therapy has been at least partly successful in terms of developing …
Although the prevalence of dementia continues to increase worldwide, incidence in the western world might have decreased as a result of better vascular care and improved brain …
RM Anderson, C Hadjichrysanthou, S Evans… - The Lancet, 2017 - thelancet.com
Alzheimer's disease is an irreversible, progressive brain disorder that accounts for about 50– 75% of all cases of dementia. 1 Alzheimer's disease is characterised by the presence of …
An estimated 24 million people worldwide have dementia, the majority of whom are thought to have Alzheimer's disease. Thus, Alzheimer's disease represents a major public health …
CR Jack - The Lancet Neurology, 2022 - thelancet.com
Over the past two decades, the landscape of dementia research has changed drastically due to advances in knowledge at the molecular, cellular, animal, and human levels …
K Blennow, MJ de Leon, H Zetterberg - The Lancet, 2006 - thelancet.com
Alzheimer's disease is the most common cause of dementia. Research advances have enabled detailed understanding of the molecular pathogenesis of the hallmarks of the …
Two decades ago, the established view was that ageing and Alzheimer's disease arise from distinct pathophysiological processes. Tremendous scientific efforts were underway to …
Background Recent estimates suggesting that over half of Alzheimer's disease burden worldwide might be attributed to potentially modifiable risk factors do not take into account …
CW Ritchie, JL Molinuevo, L Truyen, A Satlin… - The Lancet …, 2016 - thelancet.com
Alzheimer's dementia affects more than 40 million people worldwide with substantial increases in prevalence anticipated. Interventions that either modify risk or reduce the …