Background Gut microbiota composition and function are symbiotically linked with host
health and altered in metabolic, inflammatory and neurodegenerative disorders. Three …

Over the last few years, the microbiome has emerged as a high-priority research area to
discover missing links between brain health and gut dysbiosis. Emerging evidence suggests …

The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

Objectives: To comprehensively review the scientific knowledge on the gut–brain axis.
Methods: Various publications on the gut–brain axis, until 31 July 2017, were screened …

In 2016, key studies have increased our understanding of the part played by the brain–gut–
microbiota axis in disorders as diverse as depression, obesity and autism spectrum disorder …

Dopamine is a neurotransmitter that plays a critical role both peripherally and centrally in
vital functions such as cognition, reward, satiety, voluntary motor movements, pleasure, and …

The human gastrointestinal (gut) microbiota comprises diverse and dynamic populations of
bacteria, archaea, viruses, fungi, and protozoa, coexisting in a mutualistic relationship with …

A substantial body of evidence supports that the gut microbiota plays a pivotal role in the
regulation of metabolic, endocrine and immune functions. In recent years, there has been …

Experimental manipulation of the gut microbiome was found to modify emotional and
cognitive behavior, neurotransmitter expression and brain function in rodents, but …

The wealth of biotransformational capabilities encoded in the microbiome expose the host to
an array of bioactive xenobiotic products. Several of these metabolites participate in the …