Longitudinal quantification of radical bursts during pulmonary ischaemia and reperfusion

JF Gielis, GA Boulet, JJ Briedé… - European Journal of …, 2015 - academic.oup.com
OBJECTIVES Pulmonary ischaemia–reperfusion injury (IRI) is associated with several life-
threatening pulmonary disorders, and may severely compromise the outcome of lung …

[HTML][HTML] Oxidative and nitrosative stress during pulmonary ischemia-reperfusion injury: from the lab to the OR

JF Gielis, PAJ Beckers, JJ Briedé, P Cos… - Annals of …, 2017 - ncbi.nlm.nih.gov
Oxidative and nitrosative stress are an umbrella term for pathophysiological processes that
involve free radical generation during inflammation. In this review, the involvement of …

Lung ischaemia–reperfusion injury: the role of reactive oxygen species

O Pak, A Sydykov, D Kosanovic, RT Schermuly… - … redox signaling in …, 2017 - Springer
Lung ischaemia–reperfusion injury (LIRI) occurs in many lung diseases and during surgical
procedures such as lung transplantation. The re-establishment of blood flow and oxygen …

Pathogenetic role of endothelial nitric oxide synthase uncoupling during lung ischaemia–reperfusion injury

JF Gielis, L Quirynen, JJ Briedé… - European Journal of …, 2017 - academic.oup.com
OBJECTIVES: Ischaemia–reperfusion injury is a necessary part of organ transplantation and
a key determinant of both acute and chronic graft failure. We have assessed the contribution …

Temporal determination of lung NO system and COX-2 upregulation following ischemia–reperfusion injury

O Dolkart, AE, GP, W AA - Experimental lung research, 2014 - Taylor & Francis
Background: Pulmonary ischemia–reperfusion (IR) is a biopathological event detectable in
several clinical conditions, including lung transplantation, cardiopulmonary bypass …

Oxidative stress and lung ischemia‐reperfusion injury

RS Ferrari, CF Andrade - Oxidative medicine and cellular …, 2015 - Wiley Online Library
Ischemia‐reperfusion (IR) injury is directly related to the formation of reactive oxygen
species (ROS), endothelial cell injury, increased vascular permeability, and the activation of …

Inflammation and oxygen free radical formation during pulmonary ischemia-reperfusion injury

A Hamvas, R Palazzo, L Kaiser… - Journal of applied …, 1992 - journals.physiology.org
In a companion study, we showed that 2 h of warm unilateral lung ischemia followed by
reperfusion resulted in bilateral tissue injury, indicated by increases in extravascular density …

Update on ischemia-reperfusion injury in lung transplantation

F Chen, H Date - Current opinion in organ transplantation, 2015 - journals.lww.com
Update on ischemia-reperfusion injury in lung transplantatio... : Current Opinion in Organ
Transplantation Update on ischemia-reperfusion injury in lung transplantation : Current …

Inflammatory response to pulmonary ischemia–reperfusion injury

CSH Ng, S Wan, AA Arifi, APC Yim - Surgery today, 2006 - Springer
Lung ischemia–reperfusion (IR) injury is one of the most important complications following
lung transplant and cardiopulmonary bypass. The pulmonary dysfunction following lung IR …

Inducible nitric oxide synthase inhibition reverses pulmonary arterial dysfunction in lung transplantation

J Wu, H Zhu, X Chen, J Wei, X Zhang, M Xu - Inflammation Research, 2014 - Springer
Background Ischemia–reperfusion injury (IRI) after lung transplantation remains a significant
cause of morbidity and mortality. Lung IRI induces nitric oxide synthesis (iNOS) and reactive …