Objectives To investigate associations between a high genetic disease risk and disease
severity in patients with systemic lupus erythematosus (SLE). Methods Patients with SLE (n …

Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous
clinical manifestations. Recent studies have greatly expanded the number of established …

Background Systemic lupus erythematosus (SLE) is a chronic, multiorgan, autoimmune
disease that affects people of all ages and ethnicities. Objectives To explore the relationship …

Background Systemic lupus erythematosus (SLE) is a common systemic autoimmune
disease with a complex genetic inheritance. Genome-wide association studies (GWAS) …

Introduction Systemic lupus erythematosus (SLE) is a highly heterogeneous disorder,
characterized by differences in autoantibody profile, serum cytokines, and clinical …

Using three European and two Chinese genome-wide association studies (GWAS), we
investigated the performance of genetic risk scores (GRSs) for predicting the susceptibility …

We review the systemic lupus erythematosus (SLE) human genetics literature, including the
first wave of genome‐wide associations scans (GWAS), to identify confirmed and candidate …

Objectives Patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)
have increased risk of cardiovascular disease (CVD). We investigated whether single …

Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been
rapidly advanced using large-scale, case–control, candidate gene studies as well as …

Objective Systemic lupus erythematosus (SLE), an autoimmune disorder, has been
associated with nearly 100 susceptibility loci. Nevertheless, these loci only partially explain …