Adult-onset immunodeficiency syndrome due to anti-interferon (IFN)-γ autoantibodies has
attracted much attention in recent years. It usually occurs in previously healthy people and …

Background Neutralizing anti-interferon (IFN)-γ autoantibodies are linked to adult-onset
immunodeficiency and opportunistic infections. Methods To explore whether anti-IFN-γ …

Objectives In this study, we aimed to study the rate of autoantibodies against type I
interferons (IFNs) in patients with COVID-19 and analyze its dependence on severity of …

Background Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
can lead to severe disease with increased morbidity and mortality among certain risk …

Neutralizing autoantibodies against type I interferons (IFNs) have been found in some
patients with critical coronavirus disease 2019 (COVID-19), the disease caused by severe …

Interferon (IFN)–specific autoantibodies have been implicated in severe coronavirus disease
2019 (COVID-19) and have been proposed as a potential driver of the persistent symptoms …

Autoantibodies (AABs) neutralizing type I interferons (IFN) underlie about 15% of cases of
critical coronavirus disease 2019 (COVID-19) pneumonia. The impact of autoimmunity …

Purpose Autoantibodies (aAbs) to type I interferons (IFNs) have been found in less than 1%
of individuals under the age of 60 in the general population, with the prevalence increasing …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR)
doubles with every 5 y of age from childhood onward. Circulating autoantibodies …

To the Editor Interferon gamma (IFNγ) is a central effector cytokine of cellular immunity. It is
mainly produced by activated T-cells, natural killer cells and to a lesser extent by …