The total number and mass of SARS-CoV-2 virions

R Sender, YM Bar-On, S Gleizer… - Proceedings of the …, 2021 - National Acad Sciences
Quantitatively describing the time course of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection within an infected individual is important for …

[HTML][HTML] Isolation, sequence, infectivity, and replication kinetics of severe acute respiratory syndrome coronavirus 2

A Banerjee, JA Nasir, P Budylowski, L Yip… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
Since its emergence in Wuhan, China, in December 2019, severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has infected≈ 6 million persons worldwide. As …

In vivo kinetics of SARS-CoV-2 infection and its relationship with a person's infectiousness

R Ke, C Zitzmann, DD Ho… - Proceedings of the …, 2021 - National Acad Sciences
The within-host viral kinetics of SARS-CoV-2 infection and how they relate to a person's
infectiousness are not well understood. This limits our ability to quantify the impact of …

Estimating infectiousness throughout SARS-CoV-2 infection course

TC Jones, G Biele, B Mühlemann, T Veith, J Schneider… - Science, 2021 - science.org
INTRODUCTION Although post facto studies have revealed the importance of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from presymptomatic …

Viral dynamics of SARS-CoV-2 variants in vaccinated and unvaccinated individuals

SM Kissler, JR Fauver, C Mack, CG Tai, MI Breban… - MedRxiv, 2021 - medrxiv.org
We estimated (1) the time from first detectable virus to peak viral concentration (proliferation
time),(2) the time from peak viral concentration to initial return to the limit of detection …

[HTML][HTML] Infectious viral load in unvaccinated and vaccinated individuals infected with ancestral, Delta or Omicron SARS-CoV-2

O Puhach, K Adea, N Hulo, P Sattonnet, C Genecand… - Nature medicine, 2022 - nature.com
Infectious viral load (VL) expelled as droplets and aerosols by infected individuals partly
determines transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Just 2% of SARS-CoV-2− positive individuals carry 90% of the virus circulating in communities

Q Yang, TK Saldi, PK Gonzales… - Proceedings of the …, 2021 - National Acad Sciences
We analyze data from the fall 2020 pandemic response efforts at the University of Colorado
Boulder, where more than 72,500 saliva samples were tested for severe acute respiratory …

[HTML][HTML] Patient-derived SARS-CoV-2 mutations impact viral replication dynamics and infectivity in vitro and with clinical implications in vivo

H Yao, X Lu, Q Chen, K Xu, Y Chen, M Cheng, K Chen… - Cell discovery, 2020 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally
with more than 33 million patients diagnosed, taking more than a million lives. Abundant …

SARS-CoV-2 Spike protein variant D614G increases infectivity and retains sensitivity to antibodies that target the receptor binding domain

L Yurkovetskiy, KE Pascal, C Tomkins-Tinch, T Nyalile… - BioRxiv, 2020 - biorxiv.org
Virus genome sequence variants that appear over the course of an outbreak can be
exploited to map the trajectory of the virus from one susceptible host to another. While such …

Kinetics of SARS-CoV-2 infection in the human upper and lower respiratory tracts and their relationship with infectiousness

R Ke, C Zitzmann, RM Ribeiro, AS Perelson - MedRxiv, 2020 - medrxiv.org
SARS-CoV-2 is a human pathogen that causes infection in both the upper respiratory tract
(URT) and the lower respiratory tract (LRT). The viral kinetics of SARS-CoV-2 infection and …