Do chemokine/chemokine receptor axes play paramount parts in trafficking and oriented locomotion of monocytes/macrophages toward the lungs of COVID-19 …

M Mahmoodi, FM Henjeroei, G Hassanshahi… - Cytokine, 2024 - Elsevier
Abstract The COVID-19 (coronavirus disease 2019) is a well-defined viral infection, resulting
from SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2). The innate immune …

Role of CCL2/CCR2 axis in the pathogenesis of COVID-19 and possible Treatments: All options on the Table

M Ranjbar, A Rahimi, Z Baghernejadan… - International …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …

Upregulation of CCR4 in activated CD8+ T cells indicates enhanced lung homing in patients with severe acute SARS‐CoV‐2 infection

S Spoerl, AN Kremer, M Aigner… - European journal of …, 2021 - Wiley Online Library
COVID‐19 is a life‐threatening disease leading to bilateral pneumonia and respiratory
failure. The underlying reasons why a smaller percentage of patients present with severe …

[HTML][HTML] Chemokine regulation during epidemic coronavirus infection

S Majumdar, PM Murphy - Frontiers in Pharmacology, 2021 - frontiersin.org
SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus-2) is the third coronavirus to
emerge as a cause of severe and frequently fatal pneumonia epidemics in humans, joining …

[HTML][HTML] The chemokines CXC, CC and C in the pathogenesis of COVID-19 disease and as surrogates of vaccine-induced innate and adaptive protective responses

MN Karimabad, G Hassanshahi, NG Kounis, V Mplani… - Vaccines, 2022 - mdpi.com
COVID-19 is one of the progressive viral pandemics that originated from East Asia. COVID-
19 or SARS-CoV-2 has been shown to be associated with a chain of physio-pathological …

Monocytes and macrophages in COVID-19: Friends and foes

S Meidaninikjeh, N Sabouni, HZ Marzouni, S Bengar… - Life sciences, 2021 - Elsevier
The COVID-19 is a novel infectious disease caused by SARS-CoV-2 and is known as a
pandemic emergency that has led to a high rate of mortality throughout the world. Evidence …

[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection

BA Khalil, NM Elemam, AA Maghazachi - Computational and structural …, 2021 - Elsevier
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …

[HTML][HTML] Monocyte migration profiles define disease severity in acute COVID-19 and unique features of long COVID

NA Scott, L Pearmain, SB Knight… - European …, 2023 - Eur Respiratory Soc
Background COVID-19 is associated with a dysregulated immune response but it is unclear
how immune dysfunction contributes to the chronic morbidity persisting in many COVID-19 …

[HTML][HTML] Cytokines and chemokines in SARS-CoV-2 infections—therapeutic strategies targeting cytokine storm

A Pum, M Ennemoser, T Adage, AJ Kungl - Biomolecules, 2021 - mdpi.com
The recently identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
virus, the cause of coronavirus disease (COVID-19) and the associated ongoing pandemic …

[HTML][HTML] Comparison of lung-homing receptor expression and activation profiles on NK cell and T cell subsets in COVID-19 and influenza

D Brownlie, I Rødahl, R Varnaite, H Asgeirsson… - Frontiers in …, 2022 - frontiersin.org
Respiratory viral infections with SARS-CoV-2 and influenza viruses commonly induce a
strong infiltration of immune cells into the human lung, with potential detrimental effects on …