The contextual brain: implications for fear conditioning, extinction and psychopathology

S Maren, KL Phan, I Liberzon - Nature reviews neuroscience, 2013 - nature.com
Contexts surround and imbue meaning to events; they are essential for recollecting the past,
interpreting the present and anticipating the future. Indeed, the brain's capacity to …

An update on contextual fear memory mechanisms: Transition between Amygdala and Hippocampus

N Chaaya, AR Battle, LR Johnson - Neuroscience & Biobehavioral …, 2018 - Elsevier
Context is an ever-present combination of discrete environmental elements capable of
influencing many psychological processes. When context is associated with an aversive …

Understanding contextual fear conditioning: insights from a two-process model

JW Rudy, NC Huff, P Matus-Amat - Neuroscience & Biobehavioral Reviews, 2004 - Elsevier
Contextual fear conditioning is an important behavioral paradigm for studying the
neurobiology of learning and memory and the mnemonic function of the hippocampus. We …

Long-term expression of human contextual fear and extinction memories involves amygdala, hippocampus and ventromedial prefrontal cortex: a reinstatement study …

TB Lonsdorf, J Haaker, R Kalisch - Social cognitive and affective …, 2014 - academic.oup.com
Human context conditioning studies have focused on acquisition and extinction. Subsequent
long-term changes in fear behaviors not only depend on associative learning processes …

Contextual fear conditioning in humans: cortical-hippocampal and amygdala contributions

RP Alvarez, A Biggs, G Chen, DS Pine… - Journal of …, 2008 - Soc Neuroscience
Functional imaging studies of cued fear conditioning in humans have mostly confirmed
findings in animals, but it is unclear whether the brain mechanisms that underlie contextual …

Contextual fear, gestalt memories, and the hippocampus

MS Fanselow - Behavioural brain research, 2000 - Elsevier
This review examines the relationship between exploration and contextual fear conditioning.
The fear acquired to places or contexts associated with aversive events is a form of …

Activity of the anterior cingulate cortex and ventral hippocampus underlie increases in contextual fear generalization

PK Cullen, TL Gilman, P Winiecki, DC Riccio… - … of Learning and …, 2015 - Elsevier
Memories for context become less specific with time resulting in animals generalizing fear
from training contexts to novel contexts. Though much attention has been given to the neural …

Adult hippocampal neurogenesis, fear generalization, and stress

A Besnard, A Sahay - Neuropsychopharmacology, 2016 - nature.com
The generalization of fear is an adaptive, behavioral, and physiological response to the
likelihood of threat in the environment. In contrast, the overgeneralization of fear, a cardinal …

Prefrontal neuronal circuits of contextual fear conditioning

RR Rozeske, S Valerio, F Chaudun… - Genes, Brain and …, 2015 - Wiley Online Library
Over the past years, numerous studies have provided a clear understanding of the neuronal
circuits and mechanisms involved in the formation, expression and extinction phases of …

Contextual and temporal modulation of extinction: behavioral and biological mechanisms

ME Bouton, RF Westbrook, KA Corcoran, S Maren - Biological psychiatry, 2006 - Elsevier
Extinction depends, at least partly, on new learning that is specific to the context in which it is
learned. Several behavioral phenomena (renewal, reinstatement, spontaneous recovery …