Salivary gland damage and hypofunction result from various disorders, including
autoimmune Sjögren's disease (SjD) and IgG4-related disease (IgG4-RD), as well as a side …

Fibrosis is presented in various physiologic and pathologic conditions of the salivary gland.
Transforming growth factor beta (TGF-β) pathway has a pivotal role in the pathogenesis of …

Transforming growth factor-β (TGF-β) is a multi-functional cytokine with a well-described role
in the regulation of tissue fibrosis and regeneration in the liver, kidney and lung …

Transforming growth factor-β (TGF-β) signaling is known to affect salivary gland physiology
by influencing branching morphogenesis, regulating ECM deposition, and controlling …

Despite a pivotal role in salivary gland development, homeostasis, and disease, the role of
salivary gland mesenchyme is not well understood. In this study, we used the Col1a1-GFP …

Development of the palate comprises sequential stages of growth, elevation, and fusion of
the palatal shelves. The mesenchymal component of palates plays a major role in early …

Although the etiology of squamous cell carcinomas of the oral mucosa is well understood,
the cellular origin and the exact molecular mechanisms leading to their formation are not …

The transforming growth factor-beta (TGF-β) family of cytokines consists of multi-functional
polypeptides that regulate a variety of cell processes, including proliferation, differentiation …

Necrotising sialometaplasia (NSM) is a non‐neoplastic lesion mainly arising in the minor
salivary glands of the oral cavity. In the clinical features, NSM shows swelling with or without …

Salivary gland hypofunction, also termed as xerostomia, is caused by radiation therapy for
head and neck cancer or Sjögren's syndrome, leading to a detrimental impact on oral health …