Ischemicstroke is a leading cause of death and disability in the United States, but recent
advances in treatments [ie, endovascular thrombectomy and tissue plasminogen activator (t …

Ischemic stroke, a devastating event caused by the blockage of a blood vessel (s) supplying
the brain, continues to affect thousands of people in the USA every year. While no true …

Over the past few decades, basic and clinical research has identified numerous risk factors
for the development of stroke and led to major improvements in health management in the …

The cerebral vascular supply is constructed to protect the cerebral hemispheres and
brainstem from the consequences of blood flow cessation. Reversal of blood flow around …

In acute ischemic stroke, abrupt vessel occlusion results in a drop in regional CBF, leading
to time-dependent compartmentalization of the ischemic brain into tissue that is irreversibly …

The consequences of cerebrovascular disease are among the leading health issues
worldwide. Large and small cerebral vessel disease can trigger stroke and contribute to the …

The blood-brain barrier (BBB) is a critical regulator of brain homeostasis. Additionally, the
BBB is the most significant obstacle to effective CNS drug delivery. It possesses specific …

Offered in print, online, and downloadable formats, this updated edition of Stroke:
Pathophysiology, Diagnosis, and Management delivers convenient access to the latest …

Ischaemic stroke is a leading cause of disability and death for which no acute treatments
exist beyond recanalization. The development of novel therapies has been repeatedly …

In an acute ischaemic stroke, understanding the dynamics of blood–brain barrier injury is of
particular importance for the prevention of symptomatic haemorrhagic transformation …