The population of adults with congenital heart disease (CHD) now exceeds the population of
children with CHD. The long-term management of these patients relies on sequential …

Background Most congenital heart diseases (CHDs) have specific hemodynamics, including
volume and pressure overload, as well as cyanosis and pulmonary hypertension …

A biomarker is any measurable, surrogate characteristic, which reflects either the presence
or the absence of a disease state. This can be a blood test, an imaging characteristic, an …

Insights and perspectives into clinical biomarker discovery in pediatric heart failure and
congenital heart disease—a narrative review - PMC Back to Top Skip to main content NIH NLM …

Every year there are more than 11000 hospitalizations related to heart failure in children
resulting in significant morbidity and mortality. Over the last two decades, our understanding …

Abstract Purpose of Review There is an increasing number of adult patients with congenital
heart disease (CHD). While several biomarkers have been validated and integrated into …

A biomarker is a characteristic that can be used as an indicator of a biological state. A
biomarker can be a clinical observation, laboratory test or an imaging parameter. In this …

Biomarkers have established an important role in the diagnosis and prognosis of heart
failure in adults, with early indications being that their sensitivity and specificity will be similar …

Introduction: Paediatric heart failure is a common clinical syndrome that may be experienced
by children with congenital heart disease (CHD) and/or cardiomyopathy. It is characterised …

Biomarkers are widely utilized in clinical medicine for their representation of numerous
biological processes by means of measurable variables. In heart failure, biomarkers such as …