The malaria parasite life cycle alternates between two hosts: a vertebrate and the female
Anopheles mosquito vector. Cell division, proliferation, and invasion are essential for …

Malaria is a devastating infectious disease that is caused by blood-borne apicomplexan
parasites of the genus Plasmodium. These pathogens have a complex lifecycle, which …

Understanding transmission biology at an individual level is a key component of intervention
strategies that target the spread of malaria parasites from human to mosquito. Gametocytes …

Malaria transmission to mosquitoes requires a developmental switch in asexually dividing
blood-stage parasites to sexual reproduction. In Plasmodium berghei, the transcription factor …

The gametocyte, or sexual blood-stage, of the malaria parasite represents the only stage of
the parasite that can be transmitted to the mosquito vector following sexual development …

Malaria parasites have evolved a complicated life cycle alternating between two hosts.
Gametocytes are produced in the vertebrate hosts and are obligatory for natural …

INTRODUCTION Plasmodium parasites, the causative agent of malaria, are single-celled
organisms with distinct morphological developmental stages each specialized to inhabit …

Irrespective of the tremendous suffering caused by malaria, a Plasmodium infection by
pathogenic blood stages is only transient and an obligate step toward the Anopheles vector …

Abstract In this review, Anil Ghosh, Marten Edwards and Marcelo Jacobs-Lorena follow the
journey of the Plasmodium parasite in the mosquito vector. At each developmental step, they …

Plasmodium parasites have a complex life cycle that includes development in the human
host as well as the Anopheles vector. Successful transmission of the parasite between its …