Sunburn cells, single standing cells with typical morphologic features occurring in UV‐
exposed skin, have been recognized as keratinocytes undergoing apoptosis following UV …

Ultraviolet radiation (UV) induces a variety of biological effects which include the induction of
programmed cell death. UV-induced apoptosis seems to represent a controlled scavenging …

Epidemiological and experimental evidences have established solar ultraviolet (UV)
radiation as the leading cause of skin cancers. Specifically, the frequency of non-melanoma …

Sunburn cells are keratinocytes undergoing apoptosis after they have received a
physiological UVB dose that irreversibly and severely damaged their DNA or other …

The incidence of nonmelanoma skin cancer including squamous cell carcinoma (SCC) and
basal cell carcinoma (BCC) has dramatically increased in the last decades, and chronic sun …

The induction of apoptosis in keratinocytes by ultraviolet (UV)-irradiation is considered to be
a protective function against skin cancer. UV-induced DNA damage is a crucial event in UVB …

UV-induced apoptosis in keratinocytes is a highly complex process in which various
molecular pathways are involved. These include the extrinsic pathway via triggering of death …

UV radiation from the sun activates both the membrane death receptor and the intrinsic or
mitochondrial apoptotic signaling pathways in epidermal keratinocytes, triggering apoptosis …

Sunburn cell (SBC) formation in the epidermis is a characteristic consequence of ultraviolet
radiation (UVR) exposure at doses around or above the minimum erythema dose. SBC have …

The transition from a normal cell to a neoplastic cell is a complex process and involves both
genetic and epigenetic changes. The process of carcinogenesis begins when the DNA is …