Interaction between job stress and the BDNF Val66Met polymorphism affects depressive symptoms in Chinese healthcare workers

SC He, S Wu, C Wang, XD Du, G Yin, Q Jia… - Journal of affective …, 2018 - Elsevier
Background Chronic exposure to job-related stress can lead to depression and BDNF
polymorphism may play an important role in this process. The role of the stress× BDNF …

Interaction between the BDNF gene rs16917237 polymorphism and job stress on job burnout of Chinese university teachers

Y Li, T Xue, J Jin, HE Wu, Y Dong, S Zhen… - Journal of Affective …, 2022 - Elsevier
Background Job burnout is related to both environmental and genetic factors. However,
previous studies on job burnout in teachers have mainly focused on potential stressors in …

The relationship between job stress and job burnout moderated by BDNF rs6265 polymorphism

H Jia, M He, X Zhang, Y Li, S He, XY Zhang - Psychopharmacology, 2021 - Springer
Rationale Job stress can lead to job burnout, and BDNF polymorphism has been found to be
involved in its psychopathological mechanism. Research needs a better understanding of …

Interaction between job stress, serum BDNF level and the BDNF rs2049046 polymorphism in job burnout

SC He, S Wu, C Wang, DM Wang, J Wang, H Xu… - Journal of affective …, 2020 - Elsevier
Background Some studies have shown that long-term exposure to job stress could result in
burnout, and BDNF polymorphism may play an important role in its psychopathological …

BDNF Val66Met polymorphism, life stress and depression: A meta-analysis of gene-environment interaction

M Zhao, L Chen, J Yang, D Han, D Fang, X Qiu… - Journal of affective …, 2018 - Elsevier
Background Depression is thought to be multifactorial in etiology, including genetic and
environmental components. While a number of gene-environment interaction studies have …

Interaction between stress and the BDNFVal66Met polymorphism in depression: a systematic review and meta-analysis

GM Hosang, C Shiles, KE Tansey, P McGuffin, R Uher - BMC medicine, 2014 - Springer
Background Major depression is a disabling psychiatric illness with complex origins. Life
stress (childhood adversity and recent stressful events) is a robust risk factor for depression …

[HTML][HTML] Association between the BDNF Val66Met polymorphism and major depressive disorder: a systematic review and meta-analysis

Y Wang, O Li, N Li, Z Sha, Z Zhao, J Xu - Frontiers in Psychiatry, 2023 - frontiersin.org
Study objectives This meta-analysis analytically reviewed recent studies concerning the
potential associations between the brain-derived neurotrophic factor (BDNF) Val66Met …

Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity

M Verhagen, A Van Der Meij, PAM Van Deurzen… - Molecular …, 2010 - nature.com
Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that has antidepressant-
like effects in animals and may be implicated in the etiology of mood-related phenotypes …

[HTML][HTML] Genetic role of BDNF Val66Met and 5-HTTLPR polymorphisms on depressive disorder

KY Lee, SH Jeong, SH Kim, YM Ahn, YS Kim… - Psychiatry …, 2014 - ncbi.nlm.nih.gov
Objective We investigated possible association between depressive disorders and BDNF
Val66Met and 5-HTTLPR. Brain derived neurotrophic factor (BDNF) gene and serotonin …

Interacting effect of BDNF Val66Met polymorphism and stressful life events on adolescent depression

J Chen, X Li, M McGue - Genes, Brain and Behavior, 2012 - Wiley Online Library
There is a strong etiological link between brain‐derived neurotrophic factor and depression,
but the neurocellular mechanisms and gene–environment interactions remain obscure. This …