COVID-19 induces cytokine storm and dysfunctional hemostasis

J Charles, VA Ploplis - Current Drug Targets, 2022 - ingentaconnect.com
Background: Infection with SARS-CoV-2 leads to COVID-19 which can manifest in various
ways from asymptomatic or mild disease to acute respiratory distress syndrome. The …

Cytokine storm associated coagulation complications in COVID-19 patients: Pathogenesis and Management

SR Savla, KS Prabhavalkar, LK Bhatt - Expert review of anti …, 2021 - Taylor & Francis
ABSTRACT Introduction SARS-CoV-2, the causative agent of COVID-19, attacks the
immune system causing an exaggerated and uncontrolled release of pro-inflammatory …

Modulation of hemostasis in COVID-19; blood platelets may be important pieces in the COVID-19 puzzle

M Ulanowska, B Olas - Pathogens, 2021 - mdpi.com
Although the precise pathogenesis of coronavirus disease 2019 (COVID-19) currently
remains unknown, its complex nature is gradually being revealed. COVID-19 is a disease …

Coagulopathy in COVID-19

KU Lio, P Rali - Lung India, 2021 - journals.lww.com
Hemostatic derangement is a hallmark in severe COVID-19. Markedly elevation of D-dimer
and fibrinogen degradation product levels were observed in patients with severe COVID-19 …

COVID–19-associated coagulopathy: An exploration of mechanisms

ME Colling, Y Kanthi - Vascular Medicine, 2020 - journals.sagepub.com
An ongoing global pandemic of viral pneumonia (coronavirus disease [COVID-19]), due to
the virus SARS-CoV-2, has infected millions of people and remains a threat to many more …

Coagulation disorders in COVID-19: role of toll-like receptors

I Biswas, GA Khan - Journal of Inflammation Research, 2020 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) has spread rapidly throughout the world.
The range of the disease is broad but among hospitalized patients with COVID-19 are …

Thromboinflammation in COVID-19: Unraveling the interplay of coagulation and inflammation

EI Obeagu, GU Obeagu - Medicine, 2024 - journals.lww.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has not only challenged
global health systems but also spurred intense scientific inquiry into its pathophysiology …

[HTML][HTML] The interplay between inflammation and thrombosis in COVID-19: mechanisms, therapeutic strategies, and challenges

L Ma, J Willey - Thrombosis Update, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by a severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), can cause life-threatening pathology characterized …

SARS-CoV-2 and plasma hypercoagulability

E Steadman, M Fandaros, W Yin - Cellular and Molecular Bioengineering, 2021 - Springer
Hypercoagulability has emerged as a prominent consequence of COVID-19. This presents
challenges not only in the clinic, but also in thrombosis research. Health and safety …

Inflammation-induced coagulopathy substantially differs between COVID-19 and septic shock: a prospective observational study

M Dechamps, J De Poortere, M Martin, L Gatto… - Frontiers in …, 2022 - frontiersin.org
Critical COVID-19, like septic shock, is related to a dysregulated systemic inflammatory
reaction and is associated with a high incidence of thrombosis and microthrombosis …