The Impact of NAFLD-Related Indices on Brain Structure: Insights from Mendelian Randomization and Colocalization Analysis
C Chen, Y Fu, S Gu, J Liu, Y Zheng, Y Li - Available at SSRN 4773249 - papers.ssrn.com
Non-alcoholic fatty liver disease (NAFLD) has complex relationships with brain structure and
neuropsychiatric health. Our study seeks to unravel this complexity using two-sample …
neuropsychiatric health. Our study seeks to unravel this complexity using two-sample …
[HTML][HTML] Non-alcoholic fatty liver disease causally affects the brain cortical structure: a Mendelian randomization study
YK Lin, XR Cai, JZ Chen, HJ Hong, K Tu… - Frontiers in …, 2024 - frontiersin.org
Background Reduced brain volume, impaired cognition, and possibly a range of
psychoneurological disorders have been reported in patients with non-alcoholic fatty liver …
psychoneurological disorders have been reported in patients with non-alcoholic fatty liver …
[HTML][HTML] Bidirectional two-sample mendelian randomization analysis identifies causal associations of MRI-based cortical thickness and surface area relation to NAFLD
Z Mao, Z Gao, T Ji, S Huan, G Yin, L Chen - Lipids in Health and Disease, 2024 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) patients have exhibited extra-hepatic
neurological changes, but the causes and mechanisms remain unclear. This study …
neurological changes, but the causes and mechanisms remain unclear. This study …
Unravelling the liver-brain connection: A two-sample Mendelian randomization study investigating the causal relationship between NAFLD and cortical structure
S Jiang, J Zhang, Y Liu, T Zhang, H Zheng… - Diabetes Research and …, 2023 - Elsevier
Background Non-alcoholic fatty liver disease (NAFLD) has been linked to cognitive decline
and neuropsychiatric conditions, implying a potential connection between NAFLD and brain …
and neuropsychiatric conditions, implying a potential connection between NAFLD and brain …
[HTML][HTML] Causal effects of nonalcoholic fatty liver disease on cerebral cortical structure: a Mendelian randomization analysis
Z Mai, H Mao - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Previous studies have highlighted changes in the cerebral cortical structure and
cognitive function among nonalcoholic fatty liver disease (NAFLD) patients. However, the …
cognitive function among nonalcoholic fatty liver disease (NAFLD) patients. However, the …
Association of nonalcoholic fatty liver disease with lower brain volume in healthy middle-aged adults in the Framingham study
Importance Nonalcoholic fatty liver disease (NAFLD) is a common condition that is most
often asymptomatic. It is associated with metabolic syndrome, incident diabetes, carotid …
often asymptomatic. It is associated with metabolic syndrome, incident diabetes, carotid …
[HTML][HTML] Causal relationships between neuropsychiatric disorders and nonalcoholic fatty liver disease: A bidirectional Mendelian randomization study
S Wang, H Gao, P Lin, T Qian, L Xu - BMC gastroenterology, 2024 - Springer
Background Increasing evidences suggest that nonalcoholic fatty liver disease (NAFLD) is
associated with neuropsychiatric disorders. Nevertheless, whether there were causal …
associated with neuropsychiatric disorders. Nevertheless, whether there were causal …
[HTML][HTML] Genetically predicted fatty liver disease and risk of psychiatric disorders: A mendelian randomization study
WM Xu, HF Zhang, YH Feng, SJ Li… - World Journal of Clinical …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Non-alcoholic fatty liver disease (NAFLD) and alcohol-related liver disease
(ArLD) constitute the primary forms of chronic liver disease, and their incidence is …
(ArLD) constitute the primary forms of chronic liver disease, and their incidence is …
[HTML][HTML] Mendelian randomization studies of brain MRI yield insights into the pathogenesis of neuropsychiatric disorders
Background Observational studies have identified various associations between
neuroimaging alterations and neuropsychiatric disorders. However, whether such …
neuroimaging alterations and neuropsychiatric disorders. However, whether such …
Depression and the risk of non-alcohol fatty liver disease: Results from a cross-sectional study and a Mendelian randomization analysis
D Lv, N Han, M Yuan, W Huang, L Yan… - Journal of Affective …, 2024 - Elsevier
Background Previous studies have suggested that psychiatric factors may be pathogenic for
NAFLD. However, the association between depression and NAFLD is not been consistent …
NAFLD. However, the association between depression and NAFLD is not been consistent …