Organic anion transporting polypeptide (OATP) family transporters accept a number of drugs
and are increasingly being recognized as important factors in governing drug and …

There is convincing evidence that many organic anion transporting polypeptide (OATP)
transporters influence the pharmacokinetics and pharmacological efficacy of their substrate …

The importance of uptake transporters in determining drug disposition is increasingly
appreciated. While the focus of regulatory agencies worldwide has been on the hepatic …

Organic anion–transporting polypeptide (OATP) 1B1, OATP1B3, and OATP2B1 transporters
play an important role in hepatic drug disposition. Recently, an increasing number of studies …

Membrane transporters are now recognized as important determinants of the
transmembrane passage of drugs. Organic anion transporting polypeptides (OATP) form a …

Members of the organic anion transporting polypeptide (OATP) family are responsible for the
cellular uptake of a broad range of endogenous compounds and xenobiotics in multiple …

The importance of membrane transporters for drug pharmacokinetics has been increasingly
recognized during the last decade. Organic anion transporting polypeptide 1B1 (OATP1B1) …

There has been remarkable progress during the past decade in understanding of how
genetic variations in drug metabolizing enzymes and transporters contribute to observed …

During recent years, it has become increasingly recognized that drug transporters play
important roles in drug absorption and disposition. Organic anion transporting polypeptides …

Objective The uptake carrier organic anion-transporting polypeptide 1B3 (OATP1B3, gene
SLCO1B3) is involved in the hepatic clearance of xenobiotics including statins, taxanes, and …