Current concepts on immunopathogenesis of hepatitis B virus infection

H Peeridogaheh, Z Meshkat, S Habibzadeh… - Virus research, 2018 - Elsevier
Hepatitis B virus (HBV) infection is a leading cause of liver damage and hepatic
inflammation. Upon infection, effective antiviral responses by CD8+ T cells, CD4+ T cells …

Cytokine-mediated immunopathogenesis of hepatitis B virus infections

X Li, X Liu, L Tian, Y Chen - Clinical reviews in allergy & immunology, 2016 - Springer
Hepatitis B virus (HBV) infection is a worldwide health problem, with approximately one third
of populations have been infected, among which 3–5% of adults and more than 90% of …

Innate immune responses in hepatitis B virus (HBV) infection

A Busca, A Kumar - Virology journal, 2014 - Springer
Hepatitis B virus (HBV) infection has a low rate of chronicity compared to HCV infection, but
chronic liver inflammation can evolve to life threatening complications. Experimental data …

[HTML][HTML] Innate immune targets of hepatitis B virus infection

ZQ Zou, L Wang, K Wang, JG Yu - World journal of hepatology, 2016 - ncbi.nlm.nih.gov
Approximately 400 million people are chronically infected with hepatitis B virus (HBV)
globally despite the widespread immunization of HBV vaccine and the development of …

Interplay between the hepatitis B virus and innate immunity: from an understanding to the development of therapeutic concepts

S Faure-Dupuy, J Lucifora, D Durantel - Viruses, 2017 - mdpi.com
The hepatitis B virus (HBV) infects hepatocytes, which are the main cell type composing a
human liver. However, the liver is enriched with immune cells, particularly innate cells (eg …

Pathogenetic and antiviral immune responses against hepatitis B virus

M Iannacone, G Sitia, LG Guidotti - Future Virology, 2006 - Taylor & Francis
Hepatitis B virus (HBV) is a noncytopathic virus that causes liver disease of variable duration
and severity. It is widely assumed that during HBV infection the host immune response is …

Immunopathogenesis of hepatitis B virus infection

JJ Chang, SR Lewin - Immunology and cell biology, 2007 - Wiley Online Library
Hepatitis B virus (HBV) infection is a non‐cytopathic hepatotropic virus that can lead to
severe liver disease including acute hepatitis, cirrhosis and hepatocellular carcinoma …

Innate antiviral immune responses to hepatitis B virus

M Ait-Goughoulte, J Lucifora, F Zoulim, D Durantel - Viruses, 2010 - mdpi.com
Hepatitis B virus (HBV) is a major cause of acute and chronic hepatitis in humans. As HBV
itself is currently viewed as a non-cytopathic virus, the liver pathology associated with …

Control of hepatitis B virus by cytokines

Y Xia, U Protzer - Viruses, 2017 - mdpi.com
Hepatitis B virus (HBV) infection remains a major public health problem worldwide with more
than 240 million individuals chronically infected. Current treatments can control HBV …

[HTML][HTML] Innate immune recognition of hepatitis B virus

HY Liu, XY Zhang - World Journal of Hepatology, 2015 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) is a hepatotropic DNA virus and its infection results in acute or
chronic hepatitis. It is reported that the host innate immune system contributes to viral control …