Nano and microparticles as potential oral vaccine carriers and adjuvants against infectious diseases

SD Jazayeri, HX Lim, K Shameli, SK Yeap… - Frontiers in …, 2021 - frontiersin.org
Mucosal surfaces are the first site of infection for most infectious diseases and oral
vaccination can provide protection as the first line of defense. Unlike systemic …

Oral delivery of nanoparticle-based vaccines

N Marasini, M Skwarczynski, I Toth - Expert Review of Vaccines, 2014 - Taylor & Francis
Most infectious diseases are caused by pathogenic infiltrations from the mucosal tract.
Therefore, vaccines delivered to the mucosal tissues can mimic natural infections and …

[HTML][HTML] Tailoring functional nanoparticles for oral vaccine delivery: recent advances and future perspectives

P Cao, ZP Xu, L Li - Composites Part B: Engineering, 2022 - Elsevier
The oral vaccine has attracted much interest due to easy administration, induction of local
and systemic immune responses, and pain relief. Nowadays, functional nanoparticles and …

Adjuvants and delivery systems based on polymeric nanoparticles for mucosal vaccines

Z Jin, S Gao, X Cui, D Sun, K Zhao - International journal of pharmaceutics, 2019 - Elsevier
Most pathogens enter the body through mucosal surfaces. Therefore, vaccination through
the mucosal route can greatly enhance the mucosal immune response. Vaccination via the …

Nanoparticles for mucosal vaccine delivery

A Thakur, C Foged - Nanoengineered biomaterials for advanced drug …, 2020 - Elsevier
Mucosal surfaces represent important routes of entry into the human body for the majority of
pathogens, and they constitute unique sites for targeted vaccine delivery. Nanoparticle …

Nanovaccines for oral delivery-formulation strategies and challenges

S Karandikar, A Mirani, V Waybhase… - Nanostructures for Oral …, 2017 - Elsevier
The specialized field of research in vaccination is experiencing potential advances. The
majority of the currently used vaccines are administered by parenteral route. This route …

[HTML][HTML] The mucoadhesive nanoparticle-based delivery system in the development of mucosal vaccines

K Zhao, Y Xie, X Lin, W Xu - International Journal of Nanomedicine, 2022 - ncbi.nlm.nih.gov
Mucosal tissue constitutes the largest interface between the body and the external
environment, regulating the entry of pathogens, particles, and molecules. Mucosal …

Nanotechnology solutions for mucosal immunization

S Chadwick, C Kriegel, M Amiji - Advanced drug delivery reviews, 2010 - Elsevier
The current prevalence of infectious diseases in many developing regions of the world is a
serious burden, impacting both the general health as well as economic growth of these …

Polymer nanotechnology based approaches in mucosal vaccine delivery: challenges and opportunities

R Sharma, U Agrawal, N Mody, SP Vyas - Biotechnology advances, 2015 - Elsevier
Mucosal sites serve as the main portal for the entry of pathogens and thus immunization
through mucosal routes can greatly improve the immunity. Researchers are continuously …

Advanced oral vaccine delivery strategies for improving the immunity

Y Zhang, M Li, G Du, X Chen, X Sun - Advanced Drug Delivery Reviews, 2021 - Elsevier
Infectious diseases continue to inflict a high global disease burden. The consensus is that
vaccination is the most effective option against infectious diseases. Oral vaccines have …