M Dhir, MS Zenati, A Hamad, AD Singhi… - Annals of surgical …, 2018 - Springer
Background Both FOLFIRINOX and gemcitabine/nab-paclitaxel (G-nP) are used increasingly in the neoadjuvant treatment (NAT) of pancreatic ductal adenocarcinoma …
Purpose: On the basis of the ACCORD trial, FOLFIRINOX is effective in metastatic pancreatic adenocarcinoma (PDAC), making it a rational choice for locally advanced PDAC (LA). Aims …
S van Roessel, E van Veldhuisen… - JAMA …, 2020 - jamanetwork.com
Importance The benefit of adjuvant chemotherapy after resection of pancreatic cancer following neoadjuvant combination treatment with folinic acid, fluorouracil, irinotecan, and …
KK Christians, S Tsai, A Mahmoud, P Ritch… - The …, 2014 - academic.oup.com
Background. Borderline resectable pancreatic cancer is best treated by multimodality therapy. FOLFIRINOX (5-fluorouracil, oxaliplatin, irinotecan, and leucovorin) tripled the …
MJ Truty, ML Kendrick, DM Nagorney, RL Smoot… - Annals of …, 2021 - journals.lww.com
Objective: To identify predictive factors associated with operative morbidity, mortality, and survival outcomes in patients with borderline resectable (BR) or locally advanced (LA) …
Abstract Background 5-fluorouracil, leucovorin, irinotecan and oxaliplatin (FOLFIRINOX) is superior to gemcitabine in patients with metastatic pancreatic cancer who have a good …
SA Ahmad, M Duong, DPS Sohal, NS Gandhi… - Annals of …, 2020 - journals.lww.com
Objective: The optimal neoadjuvant therapy for resectable pancreatic ductal adenocarcinoma (PDA) and the impact on surgical outcomes remains unclear. Methods …
Objective: The aim of this study was to determine (1) whether preoperative factors can predict resectability of borderline resectable (BR) and locally advanced (LA) pancreatic …