Background: There is great interest in understanding the viral genomic predictors of
phenotypic traits that allow influenza A viruses to adapt to or become more virulent in …

The type of host that a virus can infect, referred to as host specificity or tropism, influences
infectivity and thus is important for disease diagnosis, epidemic response, and prevention …

Assessing the pandemic risk posed by specific non-human influenza A viruses is an
important goal in public health research. As influenza virus genome sequencing becomes …

Influenza viruses pose great threats to public health and cause enormous economic losses
every year. Previous work has revealed the viral factors associated with the virulence of …

Influenza A viruses remain a significant health problem, especially when a novel subtype
emerges from the avian population to cause severe outbreaks in humans. Zoonotic viruses …

Seasonal influenza vaccines play a crucial role in saving numerous lives annually.
However, the constant evolution of the influenza A virus necessitates frequent vaccine …

Seasonal influenza viruses are constantly changing and produce a different set of circulating
strains each season. Small genetic changes can accumulate over time and result in …

The seasonal influenza (flu) vaccine is designed to protect against those influenza viruses
predicted to circulate during the upcoming flu season, but identifying which viruses are likely …

Influenza viruses mutate rapidly and can pose a threat to public health, especially to those in
vulnerable groups. Throughout history, influenza A viruses have caused pandemics …

Background Majority of influenza A viruses reside and circulate among animal populations,
seldom infecting humans due to host range restriction. Yet when some avian strains do …