Development of polymer-based nanoformulations for glioblastoma brain cancer therapy and diagnosis: An update

B Rabha, KK Bharadwaj, S Pati, BK Choudhury… - Polymers, 2021 - mdpi.com
Brain cancers, mainly high-grade gliomas/glioblastoma, are characterized by uncontrolled
proliferation and recurrence with an extremely poor prognosis. Despite various conventional …

Recent advances in nanoparticle-based approaches for the treatment of brain tumors: Opportunities and challenges

J Ahamed, BHJ Gowda, WH Almalki, N Gupta… - European Polymer …, 2023 - Elsevier
Malignant brain tumors remain to be highly fatal illnesses with a bleak outlook, as the
average survival rate for patients after receiving medical treatment is less than two years …

Targeted Polymeric Nanoparticles as a Strategy for the Treatment of Glioblastoma: A Review

GA de Paula, MC de Paula, JAP Dutra… - Current Drug …, 2024 - ingentaconnect.com
Glioblastoma multiforme is the most common and aggressive malignant tumor that affects
the central nervous system, with high mortality and low survival. Glioblastoma multiforme …

Polymeric nanoparticles for drug delivery in glioblastoma: State of the art and future perspectives

F Madani, SS Esnaashari, TJ Webster… - Journal of Controlled …, 2022 - Elsevier
Glioblastoma (GBM) is an aggressive, fatal and malignant primary brain tumor. Despite the
current standard treatment for glioblastoma patients including neurosurgical resection …

Efficacy of polymer-based nanomedicine for the treatment of brain cancer

T Naki, BA Aderibigbe - Pharmaceutics, 2022 - mdpi.com
Malignant brain tumor is a life-threatening disease with a low survival rate. The therapies
available for the treatment of brain tumor is limited by poor uptake via the blood–brain …

Polymeric nanoparticles in brain cancer therapy: A review of current approaches

CA Caraway, H Gaitsch, EE Wicks, A Kalluri, N Kunadi… - Polymers, 2022 - mdpi.com
Translation of novel therapies for brain cancer into clinical practice is of the utmost
importance as primary brain tumors are responsible for more than 200,000 deaths …

Polymeric nanoparticles for the treatment of malignant gliomas

BS Mahmoud, AH AlAmri, C McConville - Cancers, 2020 - mdpi.com
Malignant gliomas are one of the deadliest forms of brain cancer and despite advancements
in treatment, patient prognosis remains poor, with an average survival of 15 months …

Smart nanoformulations for brain cancer theranostics: challenges and promises

F Ahmad, R Varghese, S Panda, S Ramamoorthy… - Cancers, 2022 - mdpi.com
Simple Summary Brain metastases are amongst the most invasive and lethal cancers. Yet,
effective methods for their diagnosis and therapy have remained elusive. While several …

Progress and viewpoints of multifunctional composite nanomaterials for glioblastoma theranostics

MH Chan, WT Huang, A Satpathy, TY Su, M Hsiao… - Pharmaceutics, 2022 - mdpi.com
The most common malignant tumor of the brain is glioblastoma multiforme (GBM) in adults.
Many patients die shortly after diagnosis, and only 6% of patients survive more than 5 years …

Therapeutic nanomedicine for brain cancer

SY Tzeng, JJ Green - Therapeutic delivery, 2013 - Taylor & Francis
Malignant brain cancer treatment is limited by a number of barriers, including the blood–
brain barrier, transport within the brain interstitium, difficulties in delivering therapeutics …