[HTML][HTML] Mechanisms behind retinal ganglion cell loss in diabetes and therapeutic approach

MC Potilinski, V Lorenc, S Perisset… - International Journal of …, 2020 - mdpi.com
Diabetes produces several changes in the body triggered by high glycemia. Some of these
changes include altered metabolism, structural changes in blood vessels and chronic …

[HTML][HTML] The cells involved in the pathological process of diabetic retinopathy

S Yang, J Zhang, L Chen - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetic retinopathy (DR) is an expanding global health problem, the exact mechanism of
which has not yet been clarified clearly, new insights into retinal physiology indicate that …

[HTML][HTML] Diabetic neuropathy of the retina and inflammation: perspectives

G Bikbova, T Oshitari, M Bikbov - International Journal of Molecular …, 2023 - mdpi.com
A clear connection exists between diabetes and atherosclerotic cardiovascular disease.
Consequently, therapeutic approaches that target both diseases are needed. Clinical trials …

Diabetic Retinopathy: Current Understanding, Mechanisms and Treatment Strategies

M Amjad, H Gupta, R Kumar - Journal for Research in Applied Sciences …, 2024 - jrasb.com
Researchers have been assuming about the possible connection between the eye and the
central nervous system (CNS) for a considerable amount of time. This is primarily due to the …

[HTML][HTML] Advanced glycation end-products and diabetic neuropathy of the retina

T Oshitari - International journal of molecular sciences, 2023 - mdpi.com
Diabetic retinopathy is a tissue-specific neurovascular impairment of the retina in patients
with both type 1 and type 2 diabetes. Several pathological factors are involved in the …

[HTML][HTML] The pathogenesis and therapeutic approaches of diabetic neuropathy in the retina

T Oshitari - International journal of molecular sciences, 2021 - mdpi.com
Diabetic retinopathy is a major retinal disease and a leading cause of blindness in the world.
Diabetic retinopathy is a neurovascular disease that is associated with disturbances of the …

Mechanisms of neuronal cell death in AGE-exposed retinas-research and literature review

G Bikbova, T Oshitari, T Baba… - Current diabetes …, 2017 - ingentaconnect.com
Introduction: Accelerated formation of AGE due to increasing rise in blood glucose levels
leads to developments of metabolic changes, further leading to such complications as …

[HTML][HTML] Diabetic retinopathy: A matter of retinal ganglion cell homeostasis

E Catalani, D Cervia - Neural Regeneration Research, 2020 - journals.lww.com
Diabetic retinopathy (DR) is the most common complication of diabetes and the leading
cause of visual impairment in the working-age population in the Western world (http://www …

[HTML][HTML] Role of inflammation in diabetic retinopathy

A Rübsam, S Parikh, PE Fort - International journal of molecular sciences, 2018 - mdpi.com
Diabetic retinopathy is a common complication of diabetes and remains the leading cause of
blindness among the working-age population. For decades, diabetic retinopathy was …

Pathological perturbations in diabetic retinopathy: hyperglycemia, AGEs, oxidative stress and inflammatory pathways

NS Sahajpal, RK Goel, A Chaubey… - Current Protein and …, 2019 - ingentaconnect.com
Diabetic retinopathy (DR) remains the leading cause of blindness in working-aged adults
around the world. The proliferative diabetic retinopathy (PDR) and diabetic macular edema …