Macrophages are a highly heterogeneous and plastic population of cells that are crucial for
tissue repair and regeneration. This has made macrophages a particularly attractive target …

Monocytes and macrophages play a critical role in tissue development, homeostasis, and
injury repair. These innate immune cells participate in guiding vascular remodeling …

The compatibility of biomaterials is critical to their structural and biological function in
medical applications. The immune system is the first responder to tissue trauma and to a …

Tissue healing and regeneration is a complex, choreographed, spatiotemporal process
involving a plethora of cell types, the activity of which is stringently regulated in order for …

The immune system plays a critical role in wound healing and the response to biomaterials.
Biomaterials-directed regenerative immunology is an immunoengineering strategy that …

Biomaterials are becoming increasingly crucial for healthcare solutions, with extensive use
in the field of tissue engineering and drug delivery. After implantation, biomaterials trigger an …

Endogenous regeneration aims to rebuild and reinstate tissue function through enlisting
natural self-repairing processes. Promoting endogenous regeneration by reducing tissue …

Scaffolds are an integral part of the regenerative medicine field. The contact of biomaterials
with tissue, as was clearly observed over the years, induces immune reactions in a material …

Research on the foreign body response (FBR) to biomaterial implants has been focused on
the roles that the innate immune system has on mediating tolerance or rejection of implants …

All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …