Modulation of Cholesterol metabolism with Phytoremedies in Alzheimer's disease: A comprehensive Review

S Koppula, NL Wankhede, SS Sammeta… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) is a complex neurological ailment that causes cognitive decline
and memory loss. Cholesterol metabolism dysregulation has emerged as a crucial element …

Connecting the dots between hypercholesterolemia and Alzheimer's disease: a potential mechanism based on 27-hydroxycholesterol

M Wu, Y Zhai, X Liang, W Chen, R Lin, L Ma… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD), the most common cause of dementia, is a complex and
multifactorial disease involving genetic and environmental factors, with …

Novel therapeutic strategies for Alzheimer's disease targeting brain cholesterol homeostasis

NP Samant, GL Gupta - European Journal of Neuroscience, 2021 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common cause of dementia. Aβ plaques and tauopathy are two major concerns associated …

The Intersection of cerebral cholesterol metabolism and Alzheimer's disease: Mechanisms and therapeutic prospects

L Liu, J Liang, Y Liu, B Liu, X Dong, W Cai, N Zhang - Heliyon, 2024 - cell.com
Alzheimer's disease (AD) is a common neurodegenerative disease in the elderly, the exact
pathogenesis of which remains incompletely understood, and effective preventive and …

Comprehensive Insights into Pathophysiology of Alzheimer's Disease: Herbal Approaches for Mitigating Neurodegeneration.

D Sen, S Rathee, V Pandey, SK Jain… - Current Alzheimer …, 2024 - europepmc.org
Alzheimer's disease [AD] is a progressive neurodegenerative disorder characterized by
cognitive decline, memory loss, and functional impairment. Despite extensive research, the …

Cholesterol levels and cognitive impairments

ELG Moreira, J de Oliveira, RDS Prediger… - Diet and nutrition in …, 2015 - Elsevier
Accumulating evidence suggests that some dietary patterns, specifically high-fat diet,
increase the risk of developing sporadic Alzheimer's disease (AD). In this regard …

The role of cholesterol metabolism in Alzheimer's disease

JH Sun, JT Yu, L Tan - Molecular neurobiology, 2015 - Springer
Alzheimer's disease (AD) is the most common type of dementias and becoming a worldwide
problem. As the time goes by, more and more researches show that AD is related to …

Exploring new avenues for modifying course of progression of Alzheimer's disease: the rise of natural medicine

S Lye, CE Aust, LR Griffiths, F Fernandez - Journal of the Neurological …, 2021 - Elsevier
With a constantly growing elderly population worldwide, a focus on developing efficient
prevention and therapy for Alzheimer's disease (AD) seems timely and topical. Emphasis on …

Pharmacological Approaches and Herbal Interventions for Alzheimer's Disease

S Kumar, S Singh, D Rajput, B Sharma… - The Natural Products …, 2024 - ingentaconnect.com
This comprehensive review extensively examines the utilization of herbal remedies and
pharmacological techniques for managing Alzheimer's disease (AD). It delves deeply into …

Reexamining the Causes and Effects of Cholesterol Deposition in the Brains of Patients with Alzheimer's Disease

ZL Hu, YQ Yuan, Z Tong, MQ Liao, SL Yuan… - Molecular …, 2023 - Springer
Alzheimer's disease (AD) is a degenerative disease of the central nervous system.
Numerous studies have shown that imbalances in cholesterol homeostasis in the brains of …