Many specifically human psychiatric and neurological conditions have developmental origins. Rodent models are extremely valuable for the investigation of brain development …
The human brain is a large and complex organ, setting us apart from other primates. It allows us to exhibit highly sophisticated cognitive and behavioral abilities. Therefore, our …
Comparative developmental studies of the mammalian brain can identify key changes that can generate the diverse structures and functions of the brain. We have studied how the …
P Rakic - Nature Reviews Neuroscience, 2009 - nature.com
The enlargement and species-specific elaboration of the cerebral neocortex during evolution holds the secret to the mental abilities of humans; however, the genetic origin and …
Understanding the organization of the cerebral cortex remains a central focus of neuroscience. Cortical maps have relied almost exclusively on the examination of …
MA Hofman - Frontiers in neuroanatomy, 2014 - frontiersin.org
Comparative studies of the brain in mammals suggest that there are general architectural principles governing its growth and evolutionary development. We are beginning to …
MA Tosches - Annual Review of Cell and Developmental …, 2021 - annualreviews.org
With the discovery of the incredible diversity of neurons, Cajal and coworkers laid the foundation of modern neuroscience. Neuron types are not only structural units of nervous …
A Cárdenas, V Borrell - Cellular and Molecular Life Sciences, 2020 - Springer
The cerebral cortex varies dramatically in size and complexity between amniotes due to differences in neuron number and composition. These differences emerge during embryonic …
The nervous system—in particular, the brain and its cognitive abilities—is among humans' most distinctive and impressive attributes. How the nervous system has changed in the …