Increasing evidences suggest that inflammation plays a key role in the pathogenesis of
stroke, a devastating disease second only to cardiac ischemia as a cause of death …

The search for novel therapeutic agents for the management of cerebral ischemia/stroke has
become an appealing research interest in the recent past. Neuroprotective phytochemicals …

Inflammation plays a pivotal role in the pathogenesis of ischemic stroke. The inhibition of
inflammation appears to be a potential therapeutic strategy for neuro-inflammatory injury …

Ischemic stroke is one of the leading causes of mortality and disability worldwide. However,
there is a current lack of effective therapies available. As the resident macrophages of the …

The modulation of microglial polarization from the pro-inflammatory M1 to the anti-
inflammatory M2 phenotype shows promise as a therapeutic strategy for ischemic stroke …

Stroke is a leading cause of morbidity and mortality worldwide, and consists of two types,
ischemic and hemorrhagic. Currently, there is no effective treatment to increase the survival …

Chronic neuroinflammation is a pathological feature of a number of central nervous system
(CNS) diseases and is mediated by sustained activation of microglial cells, the innate …

Stroke ranks second as a leading cause of death and permanent disability globally.
Microglia, innate immune cells in the brain, respond rapidly to ischemic injury, triggering a …

Stroke is one of the most common causes of death worldwide. The subsequent development
of neuroinflammation and brain edema dramatically increases the risks associated with …

Aims: Microglia-mediated neuroinflammation plays an important role in focal ischemic
stroke, a disorder with no effective therapeutic agents. Since microglial polarization to the …